Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011650..2011921 Replicon chromosome
Accession NZ_CP110017
Organism Escherichia coli strain HE_50

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011688..2011791 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011650..2011921 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLR76_RS10020 2008807..2010246 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OLR76_RS10025 2010364..2010600 + 237 WP_001295499.1 YebV family protein -
OLR76_RS10030 2010705..2010896 + 192 WP_000457842.1 YebW family protein -
OLR76_RS10035 2010897..2011553 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2011650..2011921 + 272 - - Antitoxin
- 2011688..2011791 - 104 - - Toxin
OLR76_RS10040 2011949..2012290 - 342 WP_000976476.1 YebY family protein -
OLR76_RS10045 2012303..2013175 - 873 WP_282983552.1 copper homeostasis membrane protein CopD -
OLR76_RS10050 2013179..2013553 - 375 WP_000168747.1 CopC domain-containing protein YobA -
OLR76_RS10055 2013692..2013922 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OLR76_RS10060 2014024..2014680 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
OLR76_RS10065 2014704..2015366 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T262720 NZ_CP110017:c2011791-2011688 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT262720 NZ_CP110017:2011650-2011921 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References