Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011647..2011918 Replicon chromosome
Accession NZ_CP110016
Organism Escherichia coli strain HE_100

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011685..2011788 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011647..2011918 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLR74_RS10030 2008804..2010243 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OLR74_RS10035 2010361..2010597 + 237 WP_001295499.1 YebV family protein -
OLR74_RS10040 2010702..2010893 + 192 WP_000457842.1 YebW family protein -
OLR74_RS10045 2010894..2011550 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2011647..2011918 + 272 - - Antitoxin
- 2011685..2011788 - 104 - - Toxin
OLR74_RS10050 2011946..2012287 - 342 WP_000976476.1 YebY family protein -
OLR74_RS10055 2012300..2013172 - 873 WP_282983552.1 copper homeostasis membrane protein CopD -
OLR74_RS10060 2013176..2013550 - 375 WP_000168747.1 CopC domain-containing protein YobA -
OLR74_RS10065 2013689..2013919 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OLR74_RS10070 2014021..2014677 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
OLR74_RS10075 2014701..2015363 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T262694 NZ_CP110016:c2011788-2011685 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT262694 NZ_CP110016:2011647-2011918 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References