Detailed information of TA system TA026268

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-StbC
• Location: 23643..24313
• Replicon: plasmid pAPA03-030
• Accession: NC_017119
• Organism: Acetobacter pasteurianus IFO 3283-03

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: C7JJA1
• Locus tag: APA03_RS15565
• Protein ID: WP_012813391.1
• Coordinates: 23891..24313 (+)
• Length: 141 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: APA03_RS15560
• Protein ID: WP_041633476.1
• Coordinates: 23643..23894 (+)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APA03_RS15535	18772..19026	+	255	WP_012813384.1	hypothetical protein	-
APA03_RS16690	19122..19292	-	171	WP_162010041.1	hypothetical protein	-
APA03_RS15540	19295..19627	-	333	WP_012813386.1	hypothetical protein	-
APA03_RS15545	19731..19970	-	240	WP_012813387.1	conjugal transfer protein TraD	-
APA03_RS15550	20035..20394	-	360	WP_012813388.1	conjugal transfer protein TraD	-
APA03_RS15555	20491..23577	+	3087	WP_012813389.1	Ti-type conjugative transfer relaxase TraA	-
APA03_RS15560	23643..23894	+	252	WP_041633476.1	plasmid stabilization protein	Antitoxin
APA03_RS15565	23891..24313	+	423	WP_012813391.1	type II toxin-antitoxin system VapC family toxin	Toxin
APA03_RS15570	24313..24540	+	228	WP_012813392.1	hypothetical protein	-
APA03_RS15575	24683..26068	-	1386	WP_012813107.1	IS1380 family transposase	-
APA03_RS15580	26126..26365	-	240	WP_012813393.1	recombinase family protein	-
APA03_RS15585	26520..26993	-	474	WP_012813394.1	ParA family protein	-
APA03_RS16365	27348..27875	-	528	WP_082179792.1	helix-turn-helix domain-containing protein	-
APA03_RS15590	28082..28381	-	300	WP_012813395.1	transcriptional regulator	-
APA03_RS15595	28383..28721	-	339	WP_012813396.1	type II toxin-antitoxin system RelE/ParE family toxin	-
APA03_RS15600	28904..29188	+	285	WP_041633485.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..49961	49961

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 141 a.a.
• Molecular weight: 18090.56 Da
• Isoelectric Point: 12.9461

>T26268 WP_012813391.1 NC_017119:23891-24313 [Acetobacter pasteurianus IFO 3283-03]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 423 bp

>T26268 NC_017119:23891-24313 [Acetobacter pasteurianus IFO 3283-03]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 10784.64 Da
• Isoelectric Point: 12.7191

>AT26268 WP_041633476.1 NC_017119:23643-23894 [Acetobacter pasteurianus IFO 3283-03]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Nucleotide

• Length: 252 bp

>AT26268 NC_017119:23643-23894 [Acetobacter pasteurianus IFO 3283-03]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Structures

Toxin

• AlphaFold DB: C7JJA1