Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011646..2011917 Replicon chromosome
Accession NZ_CP110015
Organism Escherichia coli strain HE_150

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011684..2011787 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011646..2011917 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLR73_RS10015 2008803..2010242 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OLR73_RS10020 2010360..2010596 + 237 WP_001295499.1 YebV family protein -
OLR73_RS10025 2010701..2010892 + 192 WP_000457842.1 YebW family protein -
OLR73_RS10030 2010893..2011549 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2011646..2011917 + 272 - - Antitoxin
- 2011684..2011787 - 104 - - Toxin
OLR73_RS10035 2011945..2012286 - 342 WP_000976476.1 YebY family protein -
OLR73_RS10040 2012299..2013171 - 873 WP_282983552.1 copper homeostasis membrane protein CopD -
OLR73_RS10045 2013175..2013549 - 375 WP_000168747.1 CopC domain-containing protein YobA -
OLR73_RS10050 2013688..2013918 + 231 WP_000916763.1 DNA polymerase III subunit theta -
OLR73_RS10055 2014020..2014676 + 657 WP_283012275.1 carbon-nitrogen hydrolase family protein YobB -
OLR73_RS10060 2014700..2015362 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T262668 NZ_CP110015:c2011787-2011684 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT262668 NZ_CP110015:2011646-2011917 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References