Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2726184..2726718 Replicon chromosome
Accession NZ_CP110006
Organism Flavobacterium sp. N2469

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OLM47_RS11665 Protein ID WP_257682215.1
Coordinates 2726184..2726477 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OLM47_RS11670 Protein ID WP_089056144.1
Coordinates 2726470..2726718 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OLM47_RS11635 2721549..2722238 + 690 WP_089056139.1 response regulator transcription factor -
OLM47_RS11640 2722271..2722813 - 543 WP_089056140.1 hypothetical protein -
OLM47_RS11645 2722904..2723821 - 918 WP_257682214.1 2-dehydropantoate 2-reductase -
OLM47_RS11650 2723937..2725187 - 1251 WP_099718953.1 cation:dicarboxylase symporter family transporter -
OLM47_RS11660 2725665..2725958 + 294 WP_089056142.1 hypothetical protein -
OLM47_RS11665 2726184..2726477 - 294 WP_257682215.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OLM47_RS11670 2726470..2726718 - 249 WP_089056144.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OLM47_RS11675 2726818..2727267 - 450 WP_257682216.1 nuclear transport factor 2 family protein -
OLM47_RS11680 2727325..2728119 - 795 WP_099718958.1 peptidase -
OLM47_RS11685 2728228..2728884 + 657 WP_123922143.1 hypothetical protein -
OLM47_RS11690 2728945..2730030 + 1086 WP_089056148.1 DNA polymerase III subunit gamma/tau -
OLM47_RS11695 2730104..2730256 - 153 WP_257682217.1 hypothetical protein -
OLM47_RS11700 2730240..2730683 + 444 WP_257682218.1 DNA polymerase III subunit gamma/tau -
OLM47_RS11705 2730761..2731339 - 579 WP_099718961.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11443.97 Da        Isoelectric Point: 4.8258

>T262631 WP_257682215.1 NZ_CP110006:c2726477-2726184 [Flavobacterium sp. N2469]
MAKYHFTNKAVEDLADIWNYTFDEWSENQADKYYLLLLDSCQELAENPNLGKKYDTVAESLFGFKSNLHILFYQIISNTE
IEVVRILHGRMDLKSKF

Download         Length: 294 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9251.41 Da        Isoelectric Point: 8.7454

>AT262631 WP_089056144.1 NZ_CP110006:c2726718-2726470 [Flavobacterium sp. N2469]
MGRNTSISLGNHFENFIENSLSEGRFKNASEVVRAGLRLLEEEENKLLILKKAVQEGLESGRAENFDSKKHLESLKANRK
HG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References