Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2070545..2070690 Replicon chromosome
Accession NZ_CP109983
Organism Klebsiella pneumoniae strain KP424

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2070581..2070683 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2070545..2070690 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJ961_RS09890 2065675..2067735 + 2061 WP_004151449.1 oligopeptidase B -
OJ961_RS09895 2067739..2068398 - 660 WP_020324964.1 exodeoxyribonuclease X -
OJ961_RS09900 2068477..2068707 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OJ961_RS09905 2068820..2069194 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OJ961_RS09910 2069198..2070067 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
OJ961_RS09915 2070084..2070422 + 339 WP_002911404.1 YebY family protein -
- 2070545..2070690 - 146 - - Antitoxin
- 2070581..2070683 + 103 - - Toxin
OJ961_RS09920 2071059..2071202 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OJ961_RS09925 2071307..2072275 - 969 WP_004151446.1 VirK/YbjX family protein -
OJ961_RS09930 2072432..2073085 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OJ961_RS09935 2073082..2073273 - 192 WP_002911395.1 YebW family protein -
OJ961_RS09940 2073371..2073610 - 240 WP_002911393.1 YebV family protein -
OJ961_RS09945 2073726..2075159 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262606 NZ_CP109983:2070581-2070683 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT262606 NZ_CP109983:c2070690-2070545 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References