Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pasABC/RelE-HTH |
| Location | 455..929 | Replicon | plasmid pE |
| Accession | NZ_CP109978 | ||
| Organism | Klebsiella pneumoniae strain 857 | ||
Toxin (Protein)
| Gene name | pasB | Uniprot ID | A0A8J3DT22 |
| Locus tag | OI501_RS29485 | Protein ID | WP_004197762.1 |
| Coordinates | 455..721 (-) | Length | 89 a.a. |
Antitoxin (Protein)
| Gene name | pasA | Uniprot ID | S1EJF5 |
| Locus tag | OI501_RS29490 | Protein ID | WP_000879771.1 |
| Coordinates | 705..929 (-) | Length | 75 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OI501_RS29480 (OI501_29485) | 35..385 | + | 351 | WP_004197756.1 | hypothetical protein | - |
| OI501_RS29485 (OI501_29490) | 455..721 | - | 267 | WP_004197762.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OI501_RS29490 (OI501_29495) | 705..929 | - | 225 | WP_000879771.1 | DUF6290 family protein | Antitoxin |
| OI501_RS29495 (OI501_29500) | 1596..1808 | - | 213 | WP_021527181.1 | MbeD family mobilization/exclusion protein | - |
| OI501_RS29500 (OI501_29505) | 1815..2324 | - | 510 | WP_032433972.1 | MbeB family mobilization protein | - |
| OI501_RS29505 (OI501_29510) | 2359..2793 | - | 435 | Protein_5 | relaxase/mobilization nuclease domain-containing protein | - |
| OI501_RS29510 (OI501_29515) | 3002..3346 | - | 345 | WP_062955149.1 | MobC family plasmid mobilization relaxosome protein | - |
| OI501_RS29515 (OI501_29520) | 3336..3512 | - | 177 | WP_004197757.1 | hypothetical protein | - |
| OI501_RS29520 (OI501_29525) | 4668..4994 | + | 327 | WP_050516389.1 | hypothetical protein | - |
| OI501_RS29525 (OI501_29530) | 5020..5565 | + | 546 | WP_023317533.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Mobilizable plasmid | - | - | 1..5596 | 5596 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|