Detailed information of TA system TA026260

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapC-mazE/VapC-MazE
• Location: 158675..159336
• Replicon: plasmid pAPA42C_011
• Accession: NC_017104
• Organism: Acetobacter pasteurianus IFO 3283-01-42C

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: C7JIL1
• Locus tag: APA42C_RS14035
• Protein ID: WP_006115553.1
• Coordinates: 159028..159336 (-)
• Length: 103 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: C7JIL0
• Locus tag: APA42C_RS14030
• Protein ID: WP_006115554.1
• Coordinates: 158675..158929 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APA42C_RS15850	154161..154379	-	219	WP_170315285.1	WGR domain-containing protein	-
APA42C_RS13985	154458..154736	-	279	WP_006115563.1	HU family DNA-binding protein	-
APA42C_RS16315	156178..156363	-	186	WP_041633309.1	hypothetical protein	-
APA42C_RS14005	156448..157263	+	816	WP_012813210.1	hypothetical protein	-
APA42C_RS14010	157276..157680	+	405	WP_006115557.1	hypothetical protein	-
APA42C_RS14015	157737..158057	-	321	WP_012813211.1	hypothetical protein	-
APA42C_RS14020	158087..158287	-	201	WP_012813212.1	hypothetical protein	-
APA42C_RS14025	158344..158673	-	330	WP_012813213.1	endoribonuclease MazF	-
APA42C_RS14030	158675..158929	-	255	WP_006115554.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
APA42C_RS14035	159028..159336	-	309	WP_006115553.1	PIN domain-containing protein	Toxin
APA42C_RS14040	159333..159605	-	273	WP_006115552.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
APA42C_RS14045	159935..160306	-	372	Protein_155	integrase core domain-containing protein	-
APA42C_RS14050	160400..161785	+	1386	WP_012813126.1	IS1380-like element IS1380A family transposase	-
APA42C_RS15865	161917..162368	+	452	Protein_157	recombinase family protein	-
APA42C_RS14055	162682..163455	-	774	WP_003631418.1	TSUP family transporter	-
APA42C_RS14060	163647..164231	+	585	Protein_159	IS701 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..191799	191799

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 103 a.a.
• Molecular weight: 15177.21 Da
• Isoelectric Point: 5.5500

>T26260 WP_006115553.1 NC_017104:c159336-159028 [Acetobacter pasteurianus IFO 3283-01-42C]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 309 bp

>T26260 NC_017104:c159336-159028 [Acetobacter pasteurianus IFO 3283-01-42C]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 12528.03 Da
• Isoelectric Point: 5.5500

>AT26260 WP_006115554.1 NC_017104:c158929-158675 [Acetobacter pasteurianus IFO 3283-01-42C]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFF

Nucleotide

• Length: 255 bp

>AT26260 NC_017104:c158929-158675 [Acetobacter pasteurianus IFO 3283-01-42C]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: A0A401X8Y0

Antitoxin

• AlphaFold DB: A0A6P1QDC4