262581

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2016911..2017056 Replicon chromosome
Accession NZ_CP109973
Organism Klebsiella pneumoniae strain 857

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2016947..2017049 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2016911..2017056 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI501_RS09915 (OI501_09915) 2012041..2014101 + 2061 WP_004151449.1 oligopeptidase B -
OI501_RS09920 (OI501_09920) 2014105..2014764 - 660 WP_002911407.1 exodeoxyribonuclease X -
OI501_RS09925 (OI501_09925) 2014843..2015073 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OI501_RS09930 (OI501_09930) 2015186..2015560 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OI501_RS09935 (OI501_09935) 2015564..2016433 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OI501_RS09940 (OI501_09940) 2016450..2016788 + 339 WP_002911404.1 YebY family protein -
- 2016911..2017056 - 146 - - Antitoxin
- 2016947..2017049 + 103 - - Toxin
OI501_RS09945 (OI501_09945) 2017424..2017567 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OI501_RS09950 (OI501_09950) 2017672..2018640 - 969 WP_004151446.1 VirK/YbjX family protein -
OI501_RS09955 (OI501_09955) 2018797..2019450 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OI501_RS09960 (OI501_09960) 2019447..2019638 - 192 WP_002911395.1 YebW family protein -
OI501_RS09965 (OI501_09965) 2019736..2019975 - 240 WP_002911393.1 YebV family protein -
OI501_RS09970 (OI501_09970) 2020091..2021524 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262581 NZ_CP109973:2016947-2017049 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT262581 NZ_CP109973:c2017056-2016911 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References