Detailed information of TA system TA262568

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 2538041..2539186
• Replicon: chromosome
• Accession: NZ_CP109965
• Organism: Catenovulum sp. TS8

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OLW01_RS11085
• Protein ID: WP_268073978.1
• Coordinates: 2538041..2538799 (-)
• Length: 253 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: OLW01_RS11090
• Protein ID: WP_268073979.1
• Coordinates: 2538824..2539186 (-)
• Length: 121 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OLW01_RS11065 (OLW01_11065)	2533802..2534077	-	276	WP_268073974.1	YrhK family protein	-
OLW01_RS11070 (OLW01_11070)	2534293..2535882	-	1590	WP_268073975.1	ABC-F family ATPase	-
OLW01_RS11075 (OLW01_11075)	2535997..2536884	-	888	WP_268073976.1	LysR family transcriptional regulator	-
OLW01_RS11080 (OLW01_11080)	2536963..2537919	+	957	WP_268073977.1	HPP family protein	-
OLW01_RS11085 (OLW01_11085)	2538041..2538799	-	759	WP_268073978.1	RES family NAD+ phosphorylase	Toxin
OLW01_RS11090 (OLW01_11090)	2538824..2539186	-	363	WP_268073979.1	DUF2384 domain-containing protein	Antitoxin
OLW01_RS11095 (OLW01_11095)	2539538..2540971	-	1434	WP_268073980.1	dihydrolipoyl dehydrogenase	-
OLW01_RS11100 (OLW01_11100)	2541048..2543000	-	1953	WP_268073981.1	pyruvate dehydrogenase complex dihydrolipoyllysine-residue acetyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (64-199)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (70-118)

Sequences

Toxin

Protein

• Length: 253 a.a.
• Molecular weight: 29165.14 Da
• Isoelectric Point: 4.9956

>T262568 WP_268073978.1 NZ_CP109965:c2538799-2538041 [Catenovulum sp. TS8]
MDLLNQCVEKIEFYSLYQAQVYRFVESQEQVATTSLVDNLDEQALLEDLLEQNKPKLEAEYQPLHYLISTPFRYPPLTHG
SRFGHQFMPSFFYASEDKLTALAEAAFYRFAFLLAMQKPYNQAVKSEHLMFSVNVKSKKAVDLTTHSLTEFIPILTDPVD
YRFSQKLGEHLTAQKQVELIRFYSARDKLSDTNRINLAIAQAKVICSTEPEQMVNWLCQSSESEVSFYSRNEAVYRFSVN
DFMVDGQFPLLA

Nucleotide

• Length: 759 bp

Antitoxin

Protein

• Length: 121 a.a.
• Molecular weight: 13282.43 Da
• Isoelectric Point: 9.9784

>AT262568 WP_268073979.1 NZ_CP109965:c2539186-2538824 [Catenovulum sp. TS8]
MSAVIQPDAAQILMKAYVNAYKALAVPSHQASKIIGVDPSTLSRKSNKGFAVDSKQAELQMHFIRLYRSLYALGGGDTEF
MQHWFSTYNKVLKGTPNELCLKIDGLLKTNGYLDAMRGKV

Nucleotide

• Length: 363 bp