Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2004703..2004848 Replicon chromosome
Accession NZ_CP109963
Organism Klebsiella pneumoniae isolate NY13307

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2004739..2004841 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2004703..2004848 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJ970_RS09850 (OJ970_09850) 1999833..2001893 + 2061 WP_004151449.1 oligopeptidase B -
OJ970_RS09855 (OJ970_09855) 2001897..2002556 - 660 WP_002911407.1 exodeoxyribonuclease X -
OJ970_RS09860 (OJ970_09860) 2002635..2002865 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OJ970_RS09865 (OJ970_09865) 2002978..2003352 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OJ970_RS09870 (OJ970_09870) 2003356..2004225 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OJ970_RS09875 (OJ970_09875) 2004242..2004580 + 339 WP_002911404.1 YebY family protein -
- 2004703..2004848 - 146 - - Antitoxin
- 2004739..2004841 + 103 - - Toxin
OJ970_RS09880 (OJ970_09880) 2005216..2005359 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OJ970_RS09885 (OJ970_09885) 2005464..2006432 - 969 WP_004151446.1 VirK/YbjX family protein -
OJ970_RS09890 (OJ970_09890) 2006589..2007242 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OJ970_RS09895 (OJ970_09895) 2007239..2007430 - 192 WP_002911395.1 YebW family protein -
OJ970_RS09900 (OJ970_09900) 2007528..2007767 - 240 WP_002911393.1 YebV family protein -
OJ970_RS09905 (OJ970_09905) 2007883..2009316 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262555 NZ_CP109963:2004739-2004841 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT262555 NZ_CP109963:c2004848-2004703 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References