Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 227848..228383 | Replicon | plasmid p3 |
| Accession | NZ_CP109956 | ||
| Organism | Escherichia coli strain NC22 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | V0VJJ7 |
| Locus tag | OI124_RS26285 | Protein ID | WP_000222760.1 |
| Coordinates | 228096..228383 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | V0VIP2 |
| Locus tag | OI124_RS26280 | Protein ID | WP_001132900.1 |
| Coordinates | 227848..228099 (+) | Length | 84 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OI124_RS26235 (222975) | 222975..223535 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| OI124_RS26240 (223671) | 223671..223883 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| OI124_RS26245 (224129) | 224129..224203 | + | 75 | Protein_235 | endonuclease | - |
| - (224459) | 224459..224520 | - | 62 | NuclAT_4 | - | - |
| - (224459) | 224459..224520 | - | 62 | NuclAT_4 | - | - |
| - (224459) | 224459..224520 | - | 62 | NuclAT_4 | - | - |
| - (224459) | 224459..224520 | - | 62 | NuclAT_4 | - | - |
| OI124_RS26250 (224564) | 224564..224713 | + | 150 | WP_001312851.1 | Hok/Gef family protein | - |
| OI124_RS26255 (224997) | 224997..225254 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| OI124_RS26260 (225271) | 225271..225522 | - | 252 | WP_223195197.1 | replication protein RepA | - |
| OI124_RS26265 (225513) | 225513..225560 | + | 48 | WP_229471593.1 | hypothetical protein | - |
| OI124_RS26270 (225553) | 225553..226035 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| OI124_RS26275 (226028) | 226028..226885 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| OI124_RS26280 (227848) | 227848..228099 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| OI124_RS26285 (228096) | 228096..228383 | + | 288 | WP_000222760.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OI124_RS26290 (228487) | 228487..228807 | + | 321 | Protein_244 | serine acetyltransferase | - |
| OI124_RS26295 (228823) | 228823..229170 | - | 348 | Protein_245 | IS1-like element IS1A family transposase | - |
| OI124_RS26300 (229259) | 229259..230281 | + | 1023 | WP_000255956.1 | IS21-like element IS100 family transposase | - |
| OI124_RS26305 (230278) | 230278..231060 | + | 783 | WP_001442137.1 | IS21-like element IS100kyp family helper ATPase IstB | - |
| OI124_RS26310 (231115) | 231115..231479 | - | 365 | Protein_248 | IS1 family transposase | - |
| OI124_RS26315 (231579) | 231579..232800 | + | 1222 | Protein_249 | ISL3 family transposase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | sitABCD | vat / iroN / iroE / iroD / iroC / iroB / iutA / iucD / iucC / iucB / iucA | 1..255823 | 255823 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|