262496

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3492793..3492938 Replicon chromosome
Accession NZ_CP109948
Organism Klebsiella pneumoniae strain KP1650

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3492800..3492902 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3492793..3492938 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OIS41_RS17400 (OIS41_17405) 3488325..3489758 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OIS41_RS17405 (OIS41_17410) 3489874..3490113 + 240 WP_002911393.1 YebV family protein -
OIS41_RS17410 (OIS41_17415) 3490211..3490402 + 192 WP_002911395.1 YebW family protein -
OIS41_RS17415 (OIS41_17420) 3490399..3491052 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OIS41_RS17420 (OIS41_17425) 3491209..3492177 + 969 WP_004151446.1 VirK/YbjX family protein -
OIS41_RS17425 (OIS41_17430) 3492282..3492425 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3492793..3492938 + 146 - - Antitoxin
- 3492800..3492902 - 103 - - Toxin
OIS41_RS17430 (OIS41_17435) 3493061..3493399 - 339 WP_002911404.1 YebY family protein -
OIS41_RS17435 (OIS41_17440) 3493416..3494285 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OIS41_RS17440 (OIS41_17445) 3494289..3494663 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OIS41_RS17445 (OIS41_17450) 3494776..3495006 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OIS41_RS17450 (OIS41_17455) 3495085..3495744 + 660 WP_002911407.1 exodeoxyribonuclease X -
OIS41_RS17455 (OIS41_17460) 3495748..3497808 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262496 NZ_CP109948:c3492902-3492800 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT262496 NZ_CP109948:3492793-3492938 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References