Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 991666..992292 Replicon chromosome
Accession NZ_CP109947
Organism Pectobacterium cacticida strain CFCC10813

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag OI450_RS04670 Protein ID WP_005976087.1
Coordinates 991666..991869 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag OI450_RS04675 Protein ID WP_264498006.1
Coordinates 991924..992292 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI450_RS04640 (OI450_04640) 987128..987466 + 339 WP_264498002.1 P-II family nitrogen regulator -
OI450_RS04645 (OI450_04645) 987506..988792 + 1287 WP_264498003.1 ammonium transporter AmtB -
OI450_RS04650 (OI450_04650) 988966..989826 - 861 WP_264498872.1 acyl-CoA thioesterase II -
OI450_RS04655 (OI450_04655) 990038..990571 + 534 WP_264498004.1 YbaY family lipoprotein -
OI450_RS04660 (OI450_04660) 990624..990944 - 321 WP_264498005.1 MGMT family protein -
OI450_RS04670 (OI450_04670) 991666..991869 - 204 WP_005976087.1 HHA domain-containing protein Toxin
OI450_RS04675 (OI450_04675) 991924..992292 - 369 WP_264498006.1 Hha toxicity modulator TomB Antitoxin
OI450_RS04680 (OI450_04680) 992987..993130 - 144 WP_264498007.1 type B 50S ribosomal protein L36 -
OI450_RS04685 (OI450_04685) 993147..993395 - 249 WP_264498008.1 type B 50S ribosomal protein L31 -
OI450_RS04690 (OI450_04690) 993633..996761 - 3129 WP_264498009.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T262486 WP_005976087.1 NZ_CP109947:c991869-991666 [Pectobacterium cacticida]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13989.70 Da        Isoelectric Point: 4.3316

>AT262486 WP_264498006.1 NZ_CP109947:c992292-991924 [Pectobacterium cacticida]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEYIATFVLTFKIKYPNESELSKQVETYL
DDTYVLFGNYGINDAELRRWQKSKTTLFGMFSGENICTPAKS

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure

References