Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 676904..677646 Replicon chromosome
Accession NZ_CP109947
Organism Pectobacterium cacticida strain CFCC10813

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag OI450_RS03180 Protein ID WP_264497749.1
Coordinates 677209..677646 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag OI450_RS03175 Protein ID WP_264497748.1
Coordinates 676904..677176 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OI450_RS03150 (OI450_03150) 672215..673723 - 1509 WP_264497744.1 amino acid ABC transporter permease/ATP-binding protein -
OI450_RS03155 (OI450_03155) 673747..674562 - 816 WP_264497745.1 transporter substrate-binding domain-containing protein -
OI450_RS03165 (OI450_03165) 675770..676285 - 516 WP_264497746.1 GNAT family N-acetyltransferase -
OI450_RS03170 (OI450_03170) 676287..676553 - 267 WP_264497747.1 DUF1778 domain-containing protein -
OI450_RS03175 (OI450_03175) 676904..677176 + 273 WP_264497748.1 DUF1778 domain-containing protein Antitoxin
OI450_RS03180 (OI450_03180) 677209..677646 + 438 WP_264497749.1 GNAT family N-acetyltransferase Toxin
OI450_RS03190 (OI450_03190) 678508..678990 - 483 WP_264497750.1 SsrA-binding protein SmpB -
OI450_RS03195 (OI450_03195) 679145..679591 + 447 WP_264497751.1 type II toxin-antitoxin system RatA family toxin -
OI450_RS03200 (OI450_03200) 679572..679862 + 291 WP_264497752.1 RnfH family protein -
OI450_RS03205 (OI450_03205) 680092..680592 + 501 WP_264497753.1 G/U mismatch-specific DNA glycosylase -
OI450_RS03210 (OI450_03210) 680669..682498 - 1830 WP_264497754.1 RNA polymerase sigma factor RpoD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 672215..699327 27112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(15-133)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 16013.58 Da        Isoelectric Point: 10.3857

>T262484 WP_264497749.1 NZ_CP109947:677209-677646 [Pectobacterium cacticida]
VVDFRSSEPSLDEWLKRKASKKQTMGASRTFVVCESGGNQVIGFYALATGSIQRQSVSGALRRNMPDPLPVLVLGRLAVD
ERYHRRGIGAGLLKDAVLRSRLVAEQVGTKALLVHALSEEAKAFYLHWGFTPSEIQPITLLLPLW

Download         Length: 438 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10300.79 Da        Isoelectric Point: 5.2185

>AT262484 WP_264497748.1 NZ_CP109947:676904-677176 [Pectobacterium cacticida]
MRTEAKEAPINIRAKSSQRELIDVAAKLLSKSRTDFILEAACREAEEVLLDQRLFLVDDSQFDAFVNALEKPVATNERLR
ALLNRKSPWE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References