Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 5743464..5744170 Replicon chromosome
Accession NC_017082
Organism Bradyrhizobium sp. S23321

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag S23_RS27220 Protein ID WP_015688040.1
Coordinates 5743745..5744170 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag S23_RS27215 Protein ID WP_015688039.1
Coordinates 5743464..5743748 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S23_RS27195 5738612..5739514 - 903 WP_015688035.1 sugar ABC transporter permease -
S23_RS27200 5739514..5740599 - 1086 WP_015688036.1 ABC transporter ATP-binding protein -
S23_RS27205 5740612..5741688 - 1077 WP_015688037.1 ABC transporter ATP-binding protein -
S23_RS27210 5741685..5743235 - 1551 WP_015688038.1 glycerol-3-phosphate dehydrogenase -
S23_RS27215 5743464..5743748 + 285 WP_015688039.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
S23_RS27220 5743745..5744170 + 426 WP_015688040.1 type II toxin-antitoxin system VapC family toxin Toxin
S23_RS27225 5744250..5745083 - 834 WP_015688041.1 DeoR/GlpR family DNA-binding transcription regulator -
S23_RS27230 5745175..5745861 - 687 WP_015688042.1 HAD-IA family hydrolase -
S23_RS27235 5746016..5746498 + 483 WP_015688043.1 nuclear transport factor 2 family protein -
S23_RS27240 5746554..5746745 - 192 WP_015688044.1 hypothetical protein -
S23_RS27245 5746967..5747377 - 411 WP_015688045.1 acyl-CoA thioesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-76)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15495.81 Da        Isoelectric Point: 5.7285

>T26248 WP_015688040.1 NC_017082:5743745-5744170 [Bradyrhizobium cosmicum]
VSLLLDTNVLSEVQRPAPSAKVLAWLDTIDEDRAFISVASIAELRRGVALLEDGRRRTALAAWLAHDLPERFAGRFLPID
HAVAERWGDLMAQSRRSGVALSVMDGFFAATALANNLTLVTRNVKDFVAFGVLLLNPWDNV

Download         Length: 426 bp

>T26248 NC_017082:5743745-5744170 [Bradyrhizobium cosmicum]
GTGAGCCTGTTGCTCGACACCAACGTGCTGTCGGAGGTTCAGCGGCCGGCGCCTTCCGCCAAAGTCCTGGCGTGGCTCGA
CACGATTGACGAGGATCGCGCCTTCATCAGCGTCGCCTCGATCGCCGAGCTCCGTCGTGGCGTCGCATTGCTGGAGGATG
GCCGCCGGCGCACGGCACTGGCCGCCTGGCTGGCCCACGATCTGCCGGAGCGCTTTGCAGGACGCTTCCTTCCGATCGAT
CACGCGGTGGCGGAGCGCTGGGGCGACCTGATGGCTCAGAGCCGCAGAAGCGGCGTTGCGTTGTCGGTCATGGACGGATT
CTTTGCCGCGACCGCGCTCGCAAACAACCTCACTCTCGTGACGCGGAACGTGAAGGATTTCGTGGCGTTCGGCGTCTTGC
TGCTCAACCCGTGGGACAACGTATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10311.56 Da        Isoelectric Point: 5.6977

>AT26248 WP_015688039.1 NC_017082:5743464-5743748 [Bradyrhizobium cosmicum]
MADRNTAPDPLPTDDTWTLANAKARLSEVVDRAQTGPQVITRHGRPNAVVVSADEWARKTARKGTLAEFLLASPLRGADL
DLERVHDAPRDEMP

Download         Length: 285 bp

>AT26248 NC_017082:5743464-5743748 [Bradyrhizobium cosmicum]
ATGGCCGACCGCAACACTGCACCCGACCCGCTTCCGACTGATGACACTTGGACGCTTGCCAACGCCAAGGCTCGCCTGTC
CGAGGTGGTCGACCGCGCCCAAACCGGCCCCCAGGTCATCACTCGCCATGGCAGGCCCAACGCCGTGGTCGTTTCCGCCG
ATGAATGGGCGCGGAAGACCGCGCGCAAAGGCACGCTGGCTGAATTCCTGCTGGCTTCGCCACTGCGCGGCGCCGACCTC
GATCTTGAACGCGTGCACGACGCCCCACGCGACGAGATGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References