262474

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) abiEi-abiEii/AbiEii-AbiEi
Location 933213..934645 Replicon chromosome
Accession NZ_CP109942
Organism Streptococcus suis strain ID35541

Toxin (Protein)


Gene name abiEi Uniprot ID A0A126UMF2
Locus tag OHM48_RS04630 Protein ID WP_024383472.1
Coordinates 933800..934645 (+) Length 282 a.a.

Antitoxin (Protein)


Gene name abiEii Uniprot ID -
Locus tag OHM48_RS04625 Protein ID WP_264490831.1
Coordinates 933213..933803 (+) Length 197 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHM48_RS04625 (OHM48_04625) 933213..933803 + 591 WP_264490831.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
OHM48_RS04630 (OHM48_04630) 933800..934645 + 846 WP_024383472.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
OHM48_RS04635 (OHM48_04635) 934707..937508 - 2802 WP_074394323.1 phage tail tip lysozyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(33-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-50)


Sequences

Toxin        


Download         Length: 282 a.a.        Molecular weight: 32435.11 Da        Isoelectric Point: 5.7531

>T262474 WP_024383472.1 NZ_CP109942:933800-934645 [Streptococcus suis]
MNKAKLTALCHKISKNTGLTFNSVMTYYFLEVILKKLSQSTYSNHYIFKGGFLLSNVIGVESRSTVDIDFLFHQITLSED
TVKQQLKEILADSKEGISFTIQSITAIKESDDYGGYRATILCQIENIKQVIHLDIATGDVVTPQPITYDYKAIFDEDNFP
IIAYTIETILAEKLQTIYSRNFLNSRSKDFYDVYILSKLKKEDIDFIQLKNACQRTFTYRETELDFAKIIELLERFKSDP
TQNQQWQNYSKKYSYTKGISLADVLDEMIRLITVLISINSD

Download         Length: 846 bp

Antitoxin


Download         Length: 197 a.a.        Molecular weight: 23182.70 Da        Isoelectric Point: 7.3107

>AT262474 WP_264490831.1 NZ_CP109942:933213-933803 [Streptococcus suis]
MSKKEILLEFIENHNGIITYKDCKALKIPTIYLTRLEKEGILYRVEKGIFLTQNGDYDEYYFFQYRYPKAIFSYISALYL
QQFTDEIPQYFDATIPRGYRFNTPPANLNIHSVSKEYSELGITLVKTPMGNEVSVYDLERIICDFVIHREKIDTELFVKT
LQHYGNYSKKNLTKLYEYATKMNTLDKVKQTLEVLV

Download         Length: 591 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A126UMF2

Antitoxin

Source ID Structure

References