Detailed information of TA system TA026247

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): BrnTA/BrnT-BrnA
• Location: 1704941..1705481
• Replicon: chromosome
• Accession: NC_017082
• Organism: Bradyrhizobium sp. S23321

Toxin (Protein)

• Gene name: brnT
• Uniprot ID: -
• Locus tag: S23_RS07850
• Protein ID: WP_015684160.1
• Coordinates: 1704941..1705201 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: brnA
• Uniprot ID: -
• Locus tag: S23_RS07855
• Protein ID: WP_015684161.1
• Coordinates: 1705188..1705481 (+)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
S23_RS07830	1700231..1701334	-	1104	WP_015684156.1	mandelate racemase/muconate lactonizing enzyme family protein	-
S23_RS07835	1701536..1702462	+	927	WP_015684157.1	SMP-30/gluconolactonase/LRE family protein	-
S23_RS07840	1702580..1703173	+	594	WP_015684158.1	GNAT family N-acetyltransferase	-
S23_RS07845	1703191..1704837	+	1647	WP_015684159.1	GMC family oxidoreductase N-terminal domain-containing protein	-
S23_RS07850	1704941..1705201	+	261	WP_015684160.1	BrnT family toxin	Toxin
S23_RS07855	1705188..1705481	+	294	WP_015684161.1	BrnA antitoxin family protein	Antitoxin
S23_RS07860	1706407..1707249	-	843	WP_015684162.1	MoxR family ATPase	-
S23_RS07865	1707343..1707588	-	246	WP_015684163.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
S23_RS07870	1707712..1708887	+	1176	WP_015684164.1	VWA domain-containing protein	-
S23_RS07875	1709016..1709429	+	414	WP_015684165.1	rhodanese-like domain-containing protein	-
S23_RS07880	1709562..1710416	+	855	WP_015684166.1	3-mercaptopyruvate sulfurtransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-79)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (20-92)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 9672.20 Da
• Isoelectric Point: 10.3460

>T26247 WP_015684160.1 NC_017082:1704941-1705201 [Bradyrhizobium cosmicum]
MKIVWDEPKRLANLDKHGLDFADLDEAFFDTALVIPSQSNSKRWIAVGASIRGVIVVVFARLGREGVSIISMRPASRSER
KLYAER

Nucleotide

• Length: 261 bp

>T26247 NC_017082:1704941-1705201 [Bradyrhizobium cosmicum]
ATGAAAATCGTCTGGGATGAACCGAAGCGGCTCGCCAACCTCGACAAGCATGGGCTGGATTTTGCCGATCTCGACGAAGC
CTTCTTCGACACCGCGCTGGTCATTCCGTCACAAAGCAACAGCAAGCGCTGGATCGCGGTCGGCGCGAGTATCCGTGGCG
TCATCGTCGTCGTATTCGCCCGGCTGGGACGCGAAGGCGTCAGCATCATCAGCATGCGACCGGCAAGCCGCAGCGAAAGG
AAACTCTATGCCGAACGCTAA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10836.51 Da
• Isoelectric Point: 11.1953

>AT26247 WP_015684161.1 NC_017082:1705188-1705481 [Bradyrhizobium cosmicum]
MPNAKKKSNYTKKDLRAVSDNPELTKADFAKARPFSEVFPDLSASIRKGRGPNKAPTKKLVSLRLSPEVVEHFKSTGPGW
QSRIDETLRKAVKRKAS

Nucleotide

• Length: 294 bp

>AT26247 NC_017082:1705188-1705481 [Bradyrhizobium cosmicum]
ATGCCGAACGCTAAGAAGAAGTCGAACTATACAAAGAAGGACCTGCGCGCGGTCAGCGATAATCCGGAGCTGACCAAGGC
CGATTTCGCCAAGGCGCGGCCCTTCTCTGAAGTCTTCCCTGATCTCAGTGCATCTATCCGCAAGGGCCGGGGGCCGAACA
AGGCGCCGACAAAGAAGCTCGTCTCCCTCCGCCTCAGCCCGGAAGTGGTCGAGCATTTCAAATCGACCGGACCGGGCTGG
CAATCGCGGATCGACGAGACCTTGCGCAAGGCGGTGAAGCGCAAGGCGTCGTGA