Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 3327537..3329200 | Replicon | chromosome |
| Accession | NC_017080 | ||
| Organism | Phycisphaera mikurensis NBRC 102666 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | PSMK_RS13415 | Protein ID | WP_199243844.1 |
| Coordinates | 3327537..3328139 (+) | Length | 201 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | I0II64 |
| Locus tag | PSMK_RS13420 | Protein ID | WP_014438162.1 |
| Coordinates | 3328136..3329200 (+) | Length | 355 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PSMK_RS13405 | 3324486..3326147 | + | 1662 | WP_014438159.1 | type I restriction-modification system subunit M | - |
| PSMK_RS13410 | 3326149..3327498 | + | 1350 | WP_075077286.1 | restriction endonuclease subunit S | - |
| PSMK_RS13415 | 3327537..3328139 | + | 603 | WP_199243844.1 | DUF4433 domain-containing protein | Toxin |
| PSMK_RS13420 | 3328136..3329200 | + | 1065 | WP_014438162.1 | macro domain-containing protein | Antitoxin |
| PSMK_RS13425 | 3329289..3332504 | + | 3216 | WP_014438163.1 | type I restriction endonuclease subunit R | - |
| PSMK_RS13430 | 3332593..3334041 | - | 1449 | WP_014438164.1 | sulfatase-like hydrolase/transferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 201 a.a. Molecular weight: 22333.46 Da Isoelectric Point: 6.4917
>T26246 WP_199243844.1 NC_017080:3327537-3328139 [Phycisphaera mikurensis NBRC 102666]
MTHRDNLPWILEHGLHCPTSDTLDPGFVAIGREEIIDRRTRHEVSCGPGGVLADYVPFYFTPRSIMAFNIRTGFHGLTQR
DNDDLVVLVSSIPRLLEMSIGFVFYSGQAMLHESTCHADAADLTKIDWALLNAADFRNDPEDPGKKGRYQAEALVHRHTP
VEALLGVGCYSPKVAHEVDLLVQRSGRDLAVKPAPKLFFR
MTHRDNLPWILEHGLHCPTSDTLDPGFVAIGREEIIDRRTRHEVSCGPGGVLADYVPFYFTPRSIMAFNIRTGFHGLTQR
DNDDLVVLVSSIPRLLEMSIGFVFYSGQAMLHESTCHADAADLTKIDWALLNAADFRNDPEDPGKKGRYQAEALVHRHTP
VEALLGVGCYSPKVAHEVDLLVQRSGRDLAVKPAPKLFFR
Download Length: 603 bp
>T26246 NC_017080:3327537-3328139 [Phycisphaera mikurensis NBRC 102666]
TTGACCCACCGGGACAACCTGCCGTGGATCCTGGAGCACGGGCTGCACTGCCCGACAAGCGACACGCTGGACCCCGGCTT
CGTCGCAATCGGGCGGGAGGAGATCATCGACCGCCGCACCCGCCACGAGGTTTCGTGCGGGCCCGGCGGGGTGCTCGCGG
ACTACGTGCCGTTCTACTTCACCCCGCGGTCGATCATGGCGTTCAACATCCGCACCGGGTTCCACGGGCTGACGCAGCGT
GACAACGACGACCTCGTGGTGCTGGTGTCGTCCATCCCCCGCCTGCTGGAGATGTCCATCGGCTTCGTGTTCTACAGCGG
GCAAGCGATGCTGCACGAGAGCACCTGCCACGCCGACGCCGCGGACCTGACGAAGATCGACTGGGCCCTGCTCAACGCGG
CCGACTTCCGCAACGATCCGGAGGACCCGGGGAAGAAGGGGCGGTACCAGGCGGAGGCGCTGGTCCACCGCCACACGCCG
GTGGAGGCCTTGCTCGGCGTCGGGTGCTACAGTCCGAAGGTGGCGCACGAGGTGGATCTCCTCGTGCAGCGAAGCGGCAG
GGATCTCGCCGTCAAGCCCGCGCCGAAGCTGTTTTTCCGATGA
TTGACCCACCGGGACAACCTGCCGTGGATCCTGGAGCACGGGCTGCACTGCCCGACAAGCGACACGCTGGACCCCGGCTT
CGTCGCAATCGGGCGGGAGGAGATCATCGACCGCCGCACCCGCCACGAGGTTTCGTGCGGGCCCGGCGGGGTGCTCGCGG
ACTACGTGCCGTTCTACTTCACCCCGCGGTCGATCATGGCGTTCAACATCCGCACCGGGTTCCACGGGCTGACGCAGCGT
GACAACGACGACCTCGTGGTGCTGGTGTCGTCCATCCCCCGCCTGCTGGAGATGTCCATCGGCTTCGTGTTCTACAGCGG
GCAAGCGATGCTGCACGAGAGCACCTGCCACGCCGACGCCGCGGACCTGACGAAGATCGACTGGGCCCTGCTCAACGCGG
CCGACTTCCGCAACGATCCGGAGGACCCGGGGAAGAAGGGGCGGTACCAGGCGGAGGCGCTGGTCCACCGCCACACGCCG
GTGGAGGCCTTGCTCGGCGTCGGGTGCTACAGTCCGAAGGTGGCGCACGAGGTGGATCTCCTCGTGCAGCGAAGCGGCAG
GGATCTCGCCGTCAAGCCCGCGCCGAAGCTGTTTTTCCGATGA
Antitoxin
Download Length: 355 a.a. Molecular weight: 39438.97 Da Isoelectric Point: 6.4233
>AT26246 WP_014438162.1 NC_017080:3328136-3329200 [Phycisphaera mikurensis NBRC 102666]
MIHATDGNLLEADAEALVNTVNTVGVMGKGIALMFKERFPENFRRYAAACKREEVQTGRVFAVANEELAGPHWIYNFPTK
RHWRSPSRLEWIDEGLADLAWLLREHRVASVAVPPLGAGNGGLKWADVRPLVERHLGSLPGVDVLLYEPTQAYQNVSKTT
GKERLTLARALVAEMVRRYGVLGLDCSILEIQKLAWVLQRQIRQLGLDDPLELDFKANRYGPYSDRLRHLLDALDGSWLR
SEKRLADAEPPDTIRFAPGRERKLGEWFGAGQGFHYREAVEATDALIDGFQSPLGLEALATVGWLLDEEGVEPSLAAVRE
GIARWPAGPAAAERKAGLFGDHLLEAAIRRYTHP
MIHATDGNLLEADAEALVNTVNTVGVMGKGIALMFKERFPENFRRYAAACKREEVQTGRVFAVANEELAGPHWIYNFPTK
RHWRSPSRLEWIDEGLADLAWLLREHRVASVAVPPLGAGNGGLKWADVRPLVERHLGSLPGVDVLLYEPTQAYQNVSKTT
GKERLTLARALVAEMVRRYGVLGLDCSILEIQKLAWVLQRQIRQLGLDDPLELDFKANRYGPYSDRLRHLLDALDGSWLR
SEKRLADAEPPDTIRFAPGRERKLGEWFGAGQGFHYREAVEATDALIDGFQSPLGLEALATVGWLLDEEGVEPSLAAVRE
GIARWPAGPAAAERKAGLFGDHLLEAAIRRYTHP
Download Length: 1065 bp
>AT26246 NC_017080:3328136-3329200 [Phycisphaera mikurensis NBRC 102666]
ATGATCCACGCCACGGATGGCAATCTCCTTGAAGCGGACGCGGAAGCGCTCGTGAACACGGTCAACACCGTGGGCGTGAT
GGGCAAGGGCATCGCCCTGATGTTCAAGGAACGCTTCCCGGAGAACTTCCGGCGCTACGCCGCCGCCTGCAAGCGGGAGG
AGGTCCAGACCGGGCGCGTCTTCGCGGTGGCCAACGAGGAGCTGGCCGGGCCACACTGGATCTACAACTTCCCGACGAAG
CGGCACTGGCGGTCGCCCTCCCGGCTGGAGTGGATCGACGAGGGCCTCGCCGACCTGGCGTGGCTGCTGCGCGAGCACAG
GGTCGCCTCGGTCGCGGTCCCGCCCCTTGGGGCCGGCAACGGCGGGCTGAAGTGGGCGGACGTCCGGCCGCTGGTGGAGC
GACACCTCGGCAGCCTGCCCGGGGTCGACGTGCTGCTGTACGAGCCGACGCAGGCGTACCAGAACGTCTCGAAGACGACC
GGCAAGGAGCGGCTCACGCTGGCGCGGGCGCTGGTCGCGGAGATGGTCCGCCGCTACGGGGTGCTCGGGCTGGACTGCTC
GATCCTCGAGATCCAGAAGCTCGCTTGGGTGCTGCAGCGTCAGATCCGGCAGTTGGGCTTGGATGACCCGTTGGAGCTTG
ACTTCAAGGCCAACCGCTACGGCCCCTATTCCGACCGCCTCCGTCACCTCCTCGACGCCCTCGACGGGAGCTGGCTGCGG
AGCGAGAAGCGGCTTGCCGATGCCGAACCCCCGGACACGATCCGCTTCGCGCCCGGTCGGGAGCGAAAGCTCGGCGAGTG
GTTCGGTGCGGGGCAAGGCTTCCACTACCGAGAAGCCGTGGAGGCGACCGACGCCTTGATCGATGGCTTCCAGTCGCCGC
TGGGCCTGGAGGCGCTCGCCACGGTGGGGTGGCTCCTCGACGAGGAAGGGGTGGAGCCGAGCCTCGCGGCGGTGCGTGAG
GGCATCGCTCGCTGGCCTGCGGGGCCCGCCGCGGCCGAGCGGAAGGCGGGGCTGTTCGGCGATCACCTGCTCGAGGCCGC
CATCCGGCGGTACACGCACCCGTGA
ATGATCCACGCCACGGATGGCAATCTCCTTGAAGCGGACGCGGAAGCGCTCGTGAACACGGTCAACACCGTGGGCGTGAT
GGGCAAGGGCATCGCCCTGATGTTCAAGGAACGCTTCCCGGAGAACTTCCGGCGCTACGCCGCCGCCTGCAAGCGGGAGG
AGGTCCAGACCGGGCGCGTCTTCGCGGTGGCCAACGAGGAGCTGGCCGGGCCACACTGGATCTACAACTTCCCGACGAAG
CGGCACTGGCGGTCGCCCTCCCGGCTGGAGTGGATCGACGAGGGCCTCGCCGACCTGGCGTGGCTGCTGCGCGAGCACAG
GGTCGCCTCGGTCGCGGTCCCGCCCCTTGGGGCCGGCAACGGCGGGCTGAAGTGGGCGGACGTCCGGCCGCTGGTGGAGC
GACACCTCGGCAGCCTGCCCGGGGTCGACGTGCTGCTGTACGAGCCGACGCAGGCGTACCAGAACGTCTCGAAGACGACC
GGCAAGGAGCGGCTCACGCTGGCGCGGGCGCTGGTCGCGGAGATGGTCCGCCGCTACGGGGTGCTCGGGCTGGACTGCTC
GATCCTCGAGATCCAGAAGCTCGCTTGGGTGCTGCAGCGTCAGATCCGGCAGTTGGGCTTGGATGACCCGTTGGAGCTTG
ACTTCAAGGCCAACCGCTACGGCCCCTATTCCGACCGCCTCCGTCACCTCCTCGACGCCCTCGACGGGAGCTGGCTGCGG
AGCGAGAAGCGGCTTGCCGATGCCGAACCCCCGGACACGATCCGCTTCGCGCCCGGTCGGGAGCGAAAGCTCGGCGAGTG
GTTCGGTGCGGGGCAAGGCTTCCACTACCGAGAAGCCGTGGAGGCGACCGACGCCTTGATCGATGGCTTCCAGTCGCCGC
TGGGCCTGGAGGCGCTCGCCACGGTGGGGTGGCTCCTCGACGAGGAAGGGGTGGAGCCGAGCCTCGCGGCGGTGCGTGAG
GGCATCGCTCGCTGGCCTGCGGGGCCCGCCGCGGCCGAGCGGAAGGCGGGGCTGTTCGGCGATCACCTGCTCGAGGCCGC
CATCCGGCGGTACACGCACCCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|