Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
| Location | 11624..12171 | Replicon | plasmid pP19A_1 |
| Accession | NZ_CP109930 | ||
| Organism | Escherichia coli O6:K2:H1 strain C 691-04A | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | N8A71_RS24780 | Protein ID | WP_264427353.1 |
| Coordinates | 11908..12171 (+) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A5I3EQ05 |
| Locus tag | N8A71_RS24775 | Protein ID | WP_001674495.1 |
| Coordinates | 11624..11908 (+) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N8A71_RS24755 (6818) | 6818..8221 | + | 1404 | WP_016230922.1 | FAD-dependent tricarballylate dehydrogenase TcuA | - |
| N8A71_RS24760 (8208) | 8208..9347 | + | 1140 | WP_264427351.1 | tricarballylate utilization 4Fe-4S protein TcuB | - |
| N8A71_RS24765 (9402) | 9402..10697 | + | 1296 | WP_016230924.1 | tricarballylate/proton symporter TcuC | - |
| N8A71_RS24770 (11011) | 11011..11224 | + | 214 | Protein_12 | Tn3 family transposase | - |
| N8A71_RS24775 (11624) | 11624..11908 | + | 285 | WP_001674495.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
| N8A71_RS24780 (11908) | 11908..12171 | + | 264 | WP_264427353.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| N8A71_RS24785 (12213) | 12213..13181 | - | 969 | WP_154293854.1 | IS5-like element IS903B family transposase | - |
| N8A71_RS24790 (13203) | 13203..13565 | - | 363 | WP_064735256.1 | DegT/DnrJ/EryC1/StrS family aminotransferase | - |
| N8A71_RS24795 (14397) | 14397..14810 | + | 414 | WP_016230899.1 | hypothetical protein | - |
| N8A71_RS24800 (14812) | 14812..15591 | + | 780 | WP_001164198.1 | site-specific integrase | - |
| N8A71_RS24805 (15771) | 15771..16415 | + | 645 | WP_001144036.1 | ParA family protein | - |
| N8A71_RS24810 (16502) | 16502..16810 | + | 309 | WP_000030199.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | - | - | 1..77976 | 77976 | |
| - | flank | IS/Tn | - | - | 12213..13136 | 923 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|