Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2227900..2228168 Replicon chromosome
Accession NZ_CP109929
Organism Escherichia coli O6:K2:H1 strain C 691-04A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2228028..2228130 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2227900..2228168 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8A71_RS10440 2224452..2225114 - 663 WP_000944256.1 exodeoxyribonuclease X -
N8A71_RS10445 2225138..2225794 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
N8A71_RS10450 2225897..2226127 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N8A71_RS10455 2226266..2226640 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N8A71_RS10460 2226644..2227516 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
N8A71_RS10465 2227529..2227870 + 342 WP_000984819.1 YebY family protein -
- 2227900..2228168 - 269 - - Antitoxin
- 2228028..2228130 + 103 - - Toxin
N8A71_RS10470 2228265..2228921 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
N8A71_RS10475 2228922..2229113 - 192 WP_001317886.1 YebW family protein -
N8A71_RS10480 2229218..2229454 - 237 WP_001295499.1 YebV family protein -
N8A71_RS10485 2229572..2231011 - 1440 WP_001704100.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262400 NZ_CP109929:2228028-2228130 [Escherichia coli O6:K2:H1]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT262400 NZ_CP109929:c2228168-2227900 [Escherichia coli O6:K2:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References