Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172692..2172963 Replicon chromosome
Accession NZ_CP109924
Organism Escherichia coli O125ac:K+:H10 strain C 236-04A

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172822..2172925 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172692..2172963 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8A72_RS10530 2169247..2169909 - 663 WP_000944256.1 exodeoxyribonuclease X -
N8A72_RS10535 2169933..2170589 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein YobB -
N8A72_RS10540 2170691..2170921 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N8A72_RS10545 2171060..2171434 + 375 WP_000168738.1 CopC domain-containing protein YobA -
N8A72_RS10550 2171438..2172310 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
N8A72_RS10555 2172323..2172664 + 342 WP_000976472.1 YebY family protein -
- 2172692..2172963 - 272 - - Antitoxin
- 2172822..2172925 + 104 - - Toxin
N8A72_RS10560 2173060..2173716 + 657 WP_000812740.1 protein-serine/threonine phosphatase -
N8A72_RS10565 2173717..2173908 - 192 WP_001313035.1 YebW family protein -
N8A72_RS10570 2174013..2174249 - 237 WP_001295499.1 YebV family protein -
N8A72_RS10575 2174367..2175806 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2167190..2189578 22388


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T262380 NZ_CP109924:2172822-2172925 [Escherichia coli O125ac:K+:H10]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT262380 NZ_CP109924:c2172963-2172692 [Escherichia coli O125ac:K+:H10]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References