Detailed information of TA system TA026236

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pemIK/PRK09812-MazE
• Location: 3013704..3014296
• Replicon: chromosome
• Accession: NC_017059
• Organism: Rhodospirillum photometricum DSM 122

Toxin (Protein)

• Gene name: pemK
• Uniprot ID: -
• Locus tag: RSPPHO_RS13465
• Protein ID: WP_041795570.1
• Coordinates: 3013704..3014042 (-)
• Length: 113 a.a.

Antitoxin (Protein)

• Gene name: pemI
• Uniprot ID: H6SMJ8
• Locus tag: RSPPHO_RS13470
• Protein ID: WP_014415764.1
• Coordinates: 3014039..3014296 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSPPHO_RS13455	3010522..3011379	+	858	WP_041795569.1	PhnD/SsuA/transferrin family substrate-binding protein	-
RSPPHO_RS18055	3011394..3013610	+	2217	WP_014415763.1	PAS domain-containing protein	-
RSPPHO_RS13465	3013704..3014042	-	339	WP_041795570.1	type II toxin-antitoxin system PemK/MazF family toxin	Toxin
RSPPHO_RS13470	3014039..3014296	-	258	WP_014415764.1	antitoxin	Antitoxin
RSPPHO_RS18060	3014588..3015163	-	576	WP_051013886.1	NERD domain-containing protein	-
RSPPHO_RS18065	3015361..3015885	-	525	WP_014415765.1	hypothetical protein	-
RSPPHO_RS13480	3016603..3017133	+	531	WP_014415766.1	hypothetical protein	-
RSPPHO_RS13485	3017199..3017981	-	783	WP_014415767.1	succinate dehydrogenase iron-sulfur subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-111)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 113 a.a.
• Molecular weight: 12237.05 Da
• Isoelectric Point: 5.8103

>T26236 WP_041795570.1 NC_017059:c3014042-3013704 [Pararhodospirillum photometricum DSM 122]
MSQTPKRGDIYWVDLEPTKGREQRGHRPVLVVSPDDFNQATGLPVVLPITNGGGFARGLGFAVALVGTTTTGLVRCDQPR
VLDLTVRNGRWVETLPPDLMDEVLARLAPLFD

Nucleotide

• Length: 339 bp

>T26236 NC_017059:c3014042-3013704 [Pararhodospirillum photometricum DSM 122]
ATGAGCCAGACGCCGAAACGCGGCGATATCTATTGGGTCGATTTGGAGCCGACGAAAGGCCGGGAGCAACGCGGACACCG
GCCCGTTCTTGTTGTGTCGCCCGATGACTTCAATCAGGCGACCGGGTTGCCGGTTGTCTTGCCCATCACGAATGGAGGTG
GGTTTGCCCGGGGCCTTGGCTTTGCTGTGGCTCTTGTGGGCACGACCACCACTGGTTTGGTTCGCTGTGACCAGCCCCGC
GTACTAGATCTGACGGTCCGCAACGGTCGCTGGGTGGAAACCCTGCCGCCCGACCTCATGGATGAAGTCTTGGCAAGGCT
CGCCCCCCTTTTTGACTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9074.40 Da
• Isoelectric Point: 5.7928

>AT26236 WP_014415764.1 NC_017059:c3014296-3014039 [Pararhodospirillum photometricum DSM 122]
MHTTNLRKVGGSVMLAVPPALLDVLNLSAGGKVGLSVENGRLVVEPKVRRRYTMAELLAASDYSQPQTAEDREWGESPAV
GGELI

Nucleotide

• Length: 258 bp

>AT26236 NC_017059:c3014296-3014039 [Pararhodospirillum photometricum DSM 122]
ATGCACACGACCAATCTTCGTAAAGTTGGCGGTTCGGTGATGCTGGCGGTTCCTCCGGCGCTGCTTGATGTCCTGAATTT
ATCCGCTGGAGGGAAAGTCGGCCTCTCGGTCGAGAATGGCCGCCTTGTCGTTGAGCCAAAGGTGCGGCGTCGTTACACCA
TGGCCGAGTTGCTGGCCGCCTCTGACTATTCGCAGCCACAAACGGCCGAGGATCGGGAATGGGGGGAGTCGCCTGCCGTT
GGCGGTGAGCTGATATGA

Structures

Antitoxin

• AlphaFold DB: H6SMJ8