Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2284052..2284320 Replicon chromosome
Accession NZ_CP109921
Organism Escherichia coli O2:K2:H1 strain C 237-04

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2284180..2284282 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2284052..2284320 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7L43_RS10820 2280604..2281266 - 663 WP_000944256.1 exodeoxyribonuclease X -
N7L43_RS10825 2281290..2281946 - 657 WP_000011644.1 carbon-nitrogen hydrolase family protein YobB -
N7L43_RS10830 2282049..2282279 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N7L43_RS10835 2282418..2282792 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N7L43_RS10840 2282796..2283668 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
N7L43_RS10845 2283681..2284022 + 342 WP_000984819.1 YebY family protein -
- 2284052..2284320 - 269 - - Antitoxin
- 2284180..2284282 + 103 - - Toxin
N7L43_RS10850 2284417..2285073 + 657 WP_000812743.1 protein-serine/threonine phosphatase -
N7L43_RS10855 2285074..2285265 - 192 WP_001317886.1 YebW family protein -
N7L43_RS10860 2285370..2285606 - 237 WP_001295499.1 YebV family protein -
N7L43_RS10865 2285724..2287163 - 1440 WP_171854658.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T262356 NZ_CP109921:2284180-2284282 [Escherichia coli O2:K2:H1]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT262356 NZ_CP109921:c2284320-2284052 [Escherichia coli O2:K2:H1]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References