Detailed information of TA system TA026235

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): hicAB/UPF0150(antitoxin)
• Location: 2434035..2434711
• Replicon: chromosome
• Accession: NC_017059
• Organism: Rhodospirillum photometricum DSM 122

Toxin (Protein)

• Gene name: hicA
• Uniprot ID: -
• Locus tag: RSPPHO_RS10930
• Protein ID: WP_041795135.1
• Coordinates: 2434520..2434711 (-)
• Length: 64 a.a.

Antitoxin (Protein)

• Gene name: hicB
• Uniprot ID: H6SL06
• Locus tag: RSPPHO_RS10925
• Protein ID: WP_014415305.1
• Coordinates: 2434035..2434460 (-)
• Length: 142 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSPPHO_RS10905	2429444..2430442	-	999	WP_014415301.1	threonine-phosphate decarboxylase	-
RSPPHO_RS10910	2430511..2432382	-	1872	WP_041795127.1	cobalt chelatase	-
RSPPHO_RS10915	2432339..2433187	+	849	WP_197535602.1	major capsid protein	-
RSPPHO_RS10920	2433190..2434038	+	849	WP_041795130.1	hypothetical protein	-
RSPPHO_RS10925	2434035..2434460	-	426	WP_014415305.1	type II toxin-antitoxin system HicB family antitoxin	Antitoxin
RSPPHO_RS10930	2434520..2434711	-	192	WP_041795135.1	hypothetical protein	Toxin
RSPPHO_RS10935	2434809..2435477	+	669	WP_041795137.1	hypothetical protein	-
RSPPHO_RS10940	2435474..2435905	+	432	WP_041795140.1	hypothetical protein	-
RSPPHO_RS19965	2435973..2437142	+	1170	WP_041795142.1	hypothetical protein	-
RSPPHO_RS10950	2437039..2437572	+	534	WP_157879194.1	hypothetical protein	-
RSPPHO_RS10955	2437629..2437916	+	288	WP_014415309.1	hypothetical protein	-
RSPPHO_RS10960	2437913..2438224	+	312	WP_014415310.1	hypothetical protein	-
RSPPHO_RS10970	2438776..2438967	-	192	WP_197535653.1	helix-turn-helix domain-containing protein	-
RSPPHO_RS10975	2439017..2439295	-	279	WP_014415311.1	BrnT family toxin	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• HicB-like antitoxin of toxin-antitoxin system (4-64)

Sequences

Toxin

Protein

• Length: 64 a.a.
• Molecular weight: 7008.12 Da
• Isoelectric Point: 11.0703

>T26235 WP_041795135.1 NC_017059:c2434711-2434520 [Pararhodospirillum photometricum DSM 122]
MNTDQFERWLKNQGVLVDTKKGTGHKDLLNPANGKRSILPTHGGRKQLGTGLVERIKKDLGLK

Nucleotide

• Length: 192 bp

>T26235 NC_017059:c2434711-2434520 [Pararhodospirillum photometricum DSM 122]
ATGAACACAGACCAGTTCGAGCGTTGGCTTAAAAACCAAGGGGTCTTGGTGGACACCAAGAAAGGAACCGGACACAAAGA
CCTCTTAAACCCCGCCAACGGAAAACGATCCATCCTCCCAACGCACGGCGGCAGAAAGCAACTGGGCACGGGGTTAGTGG
AGCGGATCAAAAAGGACCTGGGGCTCAAGTAG

Antitoxin

Protein

• Length: 142 a.a.
• Molecular weight: 15222.34 Da
• Isoelectric Point: 4.6199

>AT26235 WP_014415305.1 NC_017059:c2434460-2434035 [Pararhodospirillum photometricum DSM 122]
MYAYPVEFTPDDNGTVLASVPDLPGCHTFGDDEADALGHAVDAVRTMLAALVRDREDIPLPSPTDGRPVARLPVLDSLKV
RLYLEMRAQGVSQSDLARRLGKGPKDVWRLLDLTHASKMDQIEAAFAALGLVVEASVRDAA

Nucleotide

• Length: 426 bp

>AT26235 NC_017059:c2434460-2434035 [Pararhodospirillum photometricum DSM 122]
ATGTACGCATACCCTGTCGAATTCACACCCGACGACAACGGCACCGTCCTCGCGTCTGTTCCAGACCTTCCAGGGTGCCA
CACCTTCGGCGACGACGAAGCCGACGCTCTGGGGCATGCCGTCGATGCTGTCCGGACCATGCTTGCCGCCTTGGTCCGGG
ATCGTGAAGACATCCCGTTGCCGTCGCCCACCGATGGGCGGCCCGTAGCGCGCCTGCCGGTCCTGGACAGCCTGAAAGTG
CGCCTGTACCTGGAAATGAGGGCGCAGGGTGTTTCCCAGAGCGACTTGGCCCGCCGTCTCGGGAAGGGCCCGAAGGACGT
CTGGCGCTTGTTGGATCTGACCCACGCCAGCAAGATGGACCAGATCGAGGCCGCCTTTGCCGCCCTCGGCCTGGTCGTCG
AGGCCAGCGTGCGAGACGCGGCCTAA

Structures

Antitoxin

• AlphaFold DB: H6SL06