Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/- |
Location | 3869234..3870455 | Replicon | chromosome |
Accession | NZ_CP109920 | ||
Organism | Pseudomonas aeruginosa strain PALA39 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | A0A0C7CS07 |
Locus tag | PALA39_RS18005 | Protein ID | WP_003102740.1 |
Coordinates | 3869877..3870455 (+) | Length | 193 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | PALA39_RS18000 | Protein ID | WP_003088112.1 |
Coordinates | 3869234..3869788 (+) | Length | 185 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA39_RS17975 (PALA39_03566) | 3864802..3865353 | + | 552 | WP_003450159.1 | XRE family transcriptional regulator | - |
PALA39_RS17980 (PALA39_03567) | 3865350..3865748 | - | 399 | WP_023082958.1 | NADH-quinone oxidoreductase subunit A | - |
PALA39_RS17985 (PALA39_03568) | 3865761..3866084 | - | 324 | WP_003102734.1 | multidrug efflux SMR transporter | - |
PALA39_RS17990 (PALA39_03569) | 3866415..3866876 | + | 462 | WP_003102736.1 | (2Fe-2S)-binding protein | - |
PALA39_RS17995 (PALA39_03570) | 3866881..3869076 | + | 2196 | WP_023464651.1 | xanthine dehydrogenase family protein molybdopterin-binding subunit | - |
PALA39_RS18000 (PALA39_03571) | 3869234..3869788 | + | 555 | WP_003088112.1 | helix-turn-helix transcriptional regulator | Antitoxin |
PALA39_RS18005 (PALA39_03572) | 3869877..3870455 | + | 579 | WP_003102740.1 | HD domain-containing protein | Toxin |
PALA39_RS18010 (PALA39_03573) | 3870564..3871751 | - | 1188 | WP_003102741.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
PALA39_RS18015 (PALA39_03574) | 3871741..3873912 | - | 2172 | WP_003114950.1 | type I secretion system permease/ATPase | - |
PALA39_RS18020 (PALA39_03575) | 3873902..3875179 | - | 1278 | WP_003102743.1 | TolC family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21869.70 Da Isoelectric Point: 5.3655
>T262346 WP_003102740.1 NZ_CP109920:3869877-3870455 [Pseudomonas aeruginosa]
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRDRLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
MSLELLSNRLEFLREAERLKDVLRSAHTSSGRPESTAEHSWRLCLMALAFEDQLAGLDLGKVLRMCVVHDLGEAIHGDIP
AVEQAAHPDKGEQERADLLQLTRHLDAPLRDRLLALWDEYERGESAEALAVKALDKLETLLQHTQGDNPADFDYAFNLDY
GRRYTDRAPLFKTLRELLDARTRQRLAARRDA
Download Length: 579 bp
Antitoxin
Download Length: 185 a.a. Molecular weight: 20454.63 Da Isoelectric Point: 8.1590
>AT262346 WP_003088112.1 NZ_CP109920:3869234-3869788 [Pseudomonas aeruginosa]
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
MTEPLPSSSLGPALRRWRLLHRVKQTHAAELLGVAQSTISRWESGTQALLVEERARLERLLGARLEAAADQALARLVEAN
PQPVHLICDLTHRLLACSPARAAQFGVPLGELLDRSLWPYCSEEILRQEATLEELGWRELLAPPALEFASGANASAIVPI
RRSRCRWTRMTLSDGRAVRLVETL
Download Length: 555 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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