Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 1174..1651 Replicon plasmid pAsal3_J227
Accession NZ_CP109910
Organism Aeromonas salmonicida subsp. salmonicida strain J227

Toxin (Protein)


Gene name relE Uniprot ID A0A8T8CMR8
Locus tag AXW80_RS23270 Protein ID WP_073531821.1
Coordinates 1174..1443 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID Q7X2E4
Locus tag AXW80_RS23275 Protein ID WP_005321784.1
Coordinates 1427..1651 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AXW80_RS23265 (AXW80_23195) 436..1065 - 630 WP_005321764.1 hypothetical protein -
AXW80_RS23270 (AXW80_23200) 1174..1443 - 270 WP_073531821.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AXW80_RS23275 (AXW80_23205) 1427..1651 - 225 WP_005321784.1 TraY domain-containing protein Antitoxin
AXW80_RS23280 (AXW80_23210) 3433..3849 - 417 WP_269026737.1 plasmid mobilization relaxosome protein MobC -
AXW80_RS23285 (AXW80_23215) 4465..5490 - 1026 Protein_4 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - aopP 1..8322 8322


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10358.02 Da        Isoelectric Point: 10.3800

>T262328 WP_073531821.1 NZ_CP109910:c1443-1174 [Aeromonas salmonicida subsp. salmonicida]
MAWKVELTDTAKKQLARLDKTQSQRITKYLRRIMMLENPRDAGKALTGNLRTYWRYRVGDYRVVCDIRDNDLVIVAVIIG
HRSEVYGGS

Download         Length: 270 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8686.77 Da        Isoelectric Point: 4.2712

>AT262328 WP_005321784.1 NZ_CP109910:c1651-1427 [Aeromonas salmonicida subsp. salmonicida]
MLAIRLPSEIEERLANLAQETGRTKTFYAREAILTHLEELEDYYLAERVMENVRKGEERLFSLDDVERDLGLES

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A151KEE9

References