262313

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1307814..1308345 Replicon chromosome
Accession NZ_CP109894
Organism Xylella fastidiosa subsp. fastidiosa strain CFBP8351

Toxin (Protein)


Gene name relE Uniprot ID Q87CH1
Locus tag OK118_RS05900 Protein ID WP_004090909.1
Coordinates 1308064..1308345 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID Q87CH2
Locus tag OK118_RS05895 Protein ID WP_004090907.1
Coordinates 1307814..1308077 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OK118_RS05870 (OK118_05870) 1303040..1304218 - 1179 WP_011097931.1 phage tail sheath family protein -
OK118_RS05875 (OK118_05875) 1304283..1305875 - 1593 WP_012382617.1 tail fiber domain-containing protein -
OK118_RS05880 (OK118_05880) 1305883..1306440 - 558 WP_011097610.1 phage tail protein I -
OK118_RS05885 (OK118_05885) 1306433..1307326 - 894 WP_011097611.1 baseplate J/gp47 family protein -
OK118_RS05890 (OK118_05890) 1307326..1307688 - 363 WP_014607615.1 GPW/gp25 family protein -
OK118_RS05895 (OK118_05895) 1307814..1308077 + 264 WP_004090907.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
OK118_RS05900 (OK118_05900) 1308064..1308345 + 282 WP_004090909.1 type II toxin-antitoxin system YafQ family toxin Toxin
OK118_RS05905 (OK118_05905) 1308382..1308969 - 588 WP_011097612.1 phage baseplate assembly protein V -
OK118_RS05910 (OK118_05910) 1308966..1309508 - 543 WP_011097613.1 hypothetical protein -
OK118_RS05915 (OK118_05915) 1309484..1310005 - 522 WP_011097614.1 hypothetical protein -
OK118_RS05920 (OK118_05920) 1310002..1310325 - 324 WP_012382618.1 hypothetical protein -
OK118_RS05925 (OK118_05925) 1310325..1310585 - 261 WP_012382619.1 hypothetical protein -
OK118_RS05930 (OK118_05930) 1310603..1312477 - 1875 WP_012382620.1 phage major capsid protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1294401..1341123 46722


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10936.37 Da        Isoelectric Point: 7.2205

>T262313 WP_004090909.1 NZ_CP109894:1308064-1308345 [Xylella fastidiosa subsp. fastidiosa]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVLEALTCDHPLEPRHHDHALTGDWKDHRDCHIKPDLVLIYRKPDNETL
QLVRIGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9495.95 Da        Isoelectric Point: 5.6033

>AT262313 WP_004090907.1 NZ_CP109894:1307814-1308077 [Xylella fastidiosa subsp. fastidiosa]
MSANAVVRARVDAHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNETTIAAMREARAGHLKSFDSIEALM
ADLHAED

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q87CH1

Antitoxin

Source ID Structure
AlphaFold DB Q87CH2

References