Detailed information of TA system TA026231

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumA-relB/upstrm_HI1419-dnstrm_HI1420
• Location: 1733897..1734496
• Replicon: chromosome
• Accession: NC_017059
• Organism: Rhodospirillum photometricum DSM 122

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: RSPPHO_RS07670
• Protein ID: WP_041796867.1
• Coordinates: 1734200..1734496 (-)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: RSPPHO_RS07665
• Protein ID: WP_014414704.1
• Coordinates: 1733897..1734196 (-)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
RSPPHO_RS07640	1729169..1730113	+	945	WP_041794732.1	hypothetical protein	-
RSPPHO_RS07645	1730195..1730755	+	561	WP_041796865.1	50S ribosomal protein L9	-
RSPPHO_RS07650	1730825..1731091	-	267	WP_041794733.1	DUF3861 domain-containing protein	-
RSPPHO_RS07655	1731155..1731733	-	579	WP_014414701.1	PadR family transcriptional regulator	-
RSPPHO_RS07660	1731863..1733557	-	1695	WP_014414703.1	phosphomethylpyrimidine synthase ThiC	-
RSPPHO_RS07665	1733897..1734196	-	300	WP_014414704.1	putative addiction module antidote protein	Antitoxin
RSPPHO_RS07670	1734200..1734496	-	297	WP_041796867.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
RSPPHO_RS19820	1734664..1735305	-	642	WP_157879136.1	hypothetical protein	-
RSPPHO_RS18840	1735298..1736380	-	1083	WP_081581682.1	DUF262 domain-containing protein	-
RSPPHO_RS07685	1737269..1737694	-	426	WP_014414705.1	type II toxin-antitoxin system VapC family toxin	-
RSPPHO_RS07690	1737691..1737966	-	276	WP_081581683.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
RSPPHO_RS07695	1738243..1738668	+	426	WP_014414707.1	hypothetical protein	-
RSPPHO_RS07700	1738690..1739307	+	618	WP_041794735.1	leucine-rich repeat domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (3-96)

Antitoxin

• Cro/C1-type helix-turn-helix domain (48-91)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11017.60 Da
• Isoelectric Point: 10.2090

>T26231 WP_041796867.1 NC_017059:c1734496-1734200 [Pararhodospirillum photometricum DSM 122]
MFQIIQSETFQGWLTGLKDRQAVARIHARLDRAAGGNLGDVKPVRDGVAEMRIDHGPGYRLYFIRRGRLVIVLLAGGDKS
TQDADIDRAIKIAQDWRD

Nucleotide

• Length: 297 bp

>T26231 NC_017059:c1734496-1734200 [Pararhodospirillum photometricum DSM 122]
ATGTTTCAAATCATTCAGAGCGAAACCTTTCAAGGCTGGCTGACTGGCCTGAAAGACCGGCAGGCAGTGGCCCGGATTCA
TGCCCGGCTTGATCGGGCTGCGGGTGGCAATCTTGGCGATGTGAAGCCTGTGCGTGATGGTGTTGCTGAGATGCGTATTG
ATCATGGGCCGGGCTACCGCTTGTATTTCATCCGTCGCGGACGATTGGTGATCGTTCTGCTGGCAGGTGGCGACAAGAGC
ACCCAGGATGCGGATATCGACCGTGCAATTAAAATTGCGCAGGACTGGAGGGATTGA

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 10765.16 Da
• Isoelectric Point: 4.8551

>AT26231 WP_014414704.1 NC_017059:c1734196-1733897 [Pararhodospirillum photometricum DSM 122]
MTEKFSRYDTADYLKTEEDIALYLDACLEEDPGDGSLIRTALGSIARAKGMSQLARDTGISREGLYRALSAEGNPEFSTV
MKVIRALGVKLHADIAHAS

Nucleotide

• Length: 300 bp

>AT26231 NC_017059:c1734196-1733897 [Pararhodospirillum photometricum DSM 122]
ATGACTGAGAAATTTTCGCGTTACGACACGGCCGATTACCTCAAGACCGAGGAGGACATAGCGCTTTATCTCGATGCCTG
TCTCGAGGAAGACCCCGGCGATGGCAGCCTGATCCGTACCGCGCTTGGCAGCATCGCCCGTGCCAAGGGGATGAGCCAGC
TTGCCCGCGATACGGGCATTTCCCGTGAGGGGCTTTATCGTGCGCTGTCCGCCGAGGGTAATCCAGAGTTCAGCACCGTG
ATGAAGGTGATCCGCGCCCTGGGAGTAAAACTCCACGCGGATATCGCGCACGCTTCCTGA