Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
Location | 1185217..1186013 | Replicon | chromosome |
Accession | NZ_CP109891 | ||
Organism | Xylella fastidiosa subsp. fastidiosa strain CFBP8083 |
Toxin (Protein)
Gene name | VbhT | Uniprot ID | Q87CQ8 |
Locus tag | OK113_RS05190 | Protein ID | WP_004088112.1 |
Coordinates | 1185217..1185828 (-) | Length | 204 a.a. |
Antitoxin (Protein)
Gene name | VbhA | Uniprot ID | B2I551 |
Locus tag | OK113_RS05195 | Protein ID | WP_004088114.1 |
Coordinates | 1185825..1186013 (-) | Length | 63 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OK113_RS05145 (OK113_05145) | 1180672..1181559 | - | 888 | WP_012382597.1 | YdaU family protein | - |
OK113_RS05150 (OK113_05150) | 1181556..1182344 | - | 789 | WP_011097897.1 | Bro-N domain-containing protein | - |
OK113_RS05155 (OK113_05155) | 1182341..1182973 | - | 633 | WP_004088094.1 | Bro-N domain-containing protein | - |
OK113_RS05160 (OK113_05160) | 1182970..1183233 | - | 264 | WP_228446177.1 | hypothetical protein | - |
OK113_RS05165 (OK113_05165) | 1183251..1183466 | - | 216 | WP_012382598.1 | hypothetical protein | - |
OK113_RS05170 (OK113_05170) | 1183496..1183684 | - | 189 | WP_004088102.1 | hypothetical protein | - |
OK113_RS05175 (OK113_05175) | 1183712..1183903 | - | 192 | WP_004088104.1 | hypothetical protein | - |
OK113_RS05180 (OK113_05180) | 1184162..1184407 | - | 246 | WP_004088108.1 | hypothetical protein | - |
OK113_RS05185 (OK113_05185) | 1184492..1185166 | + | 675 | WP_004088110.1 | helix-turn-helix transcriptional regulator | - |
OK113_RS05190 (OK113_05190) | 1185217..1185828 | - | 612 | WP_004088112.1 | Fic/DOC family protein | Toxin |
OK113_RS05195 (OK113_05195) | 1185825..1186013 | - | 189 | WP_004088114.1 | antitoxin VbhA family protein | Antitoxin |
OK113_RS05200 (OK113_05200) | 1186405..1186941 | + | 537 | WP_038233020.1 | hypothetical protein | - |
OK113_RS05205 (OK113_05205) | 1186938..1187351 | + | 414 | WP_004088056.1 | DUF1566 domain-containing protein | - |
OK113_RS05210 (OK113_05210) | 1187348..1187749 | + | 402 | WP_004088054.1 | hypothetical protein | - |
OK113_RS05215 (OK113_05215) | 1187746..1187895 | + | 150 | WP_012382602.1 | hypothetical protein | - |
OK113_RS05220 (OK113_05220) | 1188113..1188259 | + | 147 | WP_225621633.1 | hypothetical protein | - |
OK113_RS05225 (OK113_05225) | 1188282..1188473 | + | 192 | WP_012382603.1 | hypothetical protein | - |
OK113_RS05230 (OK113_05230) | 1188494..1188838 | + | 345 | WP_004088346.1 | hypothetical protein | - |
OK113_RS05235 (OK113_05235) | 1188878..1189699 | + | 822 | WP_004088345.1 | DUF2303 family protein | - |
OK113_RS05240 (OK113_05240) | 1189715..1190641 | + | 927 | WP_004088344.1 | phage recombination protein Bet | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1155053..1195763 | 40710 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22832.60 Da Isoelectric Point: 5.1271
>T262305 WP_004088112.1 NZ_CP109891:c1185828-1185217 [Xylella fastidiosa subsp. fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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