Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | FicTA/Fic(toxin) |
Location | 1184764..1185560 | Replicon | chromosome |
Accession | NZ_CP109890 | ||
Organism | Xylella fastidiosa subsp. fastidiosa strain WM1-1 |
Toxin (Protein)
Gene name | VbhT | Uniprot ID | Q87CQ8 |
Locus tag | OK119_RS05210 | Protein ID | WP_004088112.1 |
Coordinates | 1184764..1185375 (-) | Length | 204 a.a. |
Antitoxin (Protein)
Gene name | VbhA | Uniprot ID | B2I551 |
Locus tag | OK119_RS05215 | Protein ID | WP_004088114.1 |
Coordinates | 1185372..1185560 (-) | Length | 63 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
OK119_RS05165 (OK119_05165) | 1180219..1181106 | - | 888 | WP_012382597.1 | YdaU family protein | - |
OK119_RS05170 (OK119_05170) | 1181103..1181891 | - | 789 | WP_011097897.1 | Bro-N domain-containing protein | - |
OK119_RS05175 (OK119_05175) | 1181888..1182520 | - | 633 | WP_004088094.1 | Bro-N domain-containing protein | - |
OK119_RS05180 (OK119_05180) | 1182517..1182780 | - | 264 | WP_228446177.1 | hypothetical protein | - |
OK119_RS05185 (OK119_05185) | 1182798..1183013 | - | 216 | WP_012382598.1 | hypothetical protein | - |
OK119_RS05190 (OK119_05190) | 1183043..1183231 | - | 189 | WP_004088102.1 | hypothetical protein | - |
OK119_RS05195 (OK119_05195) | 1183259..1183450 | - | 192 | WP_004088104.1 | hypothetical protein | - |
OK119_RS05200 (OK119_05200) | 1183709..1183954 | - | 246 | WP_004088108.1 | hypothetical protein | - |
OK119_RS05205 (OK119_05205) | 1184039..1184713 | + | 675 | WP_004088110.1 | helix-turn-helix transcriptional regulator | - |
OK119_RS05210 (OK119_05210) | 1184764..1185375 | - | 612 | WP_004088112.1 | Fic/DOC family protein | Toxin |
OK119_RS05215 (OK119_05215) | 1185372..1185560 | - | 189 | WP_004088114.1 | antitoxin VbhA family protein | Antitoxin |
OK119_RS05220 (OK119_05220) | 1185952..1186488 | + | 537 | WP_038233020.1 | hypothetical protein | - |
OK119_RS05225 (OK119_05225) | 1186485..1186898 | + | 414 | WP_004088056.1 | DUF1566 domain-containing protein | - |
OK119_RS05230 (OK119_05230) | 1186895..1187296 | + | 402 | WP_004088054.1 | hypothetical protein | - |
OK119_RS05235 (OK119_05235) | 1187293..1187442 | + | 150 | WP_012382602.1 | hypothetical protein | - |
OK119_RS05240 (OK119_05240) | 1187660..1187806 | + | 147 | WP_225621633.1 | hypothetical protein | - |
OK119_RS05245 (OK119_05245) | 1187829..1188020 | + | 192 | WP_012382603.1 | hypothetical protein | - |
OK119_RS05250 (OK119_05250) | 1188041..1188385 | + | 345 | WP_004088346.1 | hypothetical protein | - |
OK119_RS05255 (OK119_05255) | 1188425..1189246 | + | 822 | WP_004088345.1 | DUF2303 family protein | - |
OK119_RS05260 (OK119_05260) | 1189262..1190188 | + | 927 | WP_004088344.1 | phage recombination protein Bet | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1154600..1195310 | 40710 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 204 a.a. Molecular weight: 22832.60 Da Isoelectric Point: 5.1271
>T262296 WP_004088112.1 NZ_CP109890:c1185375-1184764 [Xylella fastidiosa subsp. fastidiosa]
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
MKYAGDRGDPYLDSETGVLRNLLGIRDQGGLDKIESTLSFLRTSELRERPVKGKFDLAHLQEIHNRLFQDVYDWAGQIRQ
VEISKGNTMFAQQIAIQSAAQQIFGQLAKERFLCGLDAEEFSKRAGDYLGEINVLHPFREGNGRTQREFIAQLAQRAGYR
IDWGVVSQADMIKASIDAYNGDSSGLASIIREGISDQLFKDNE
Download Length: 612 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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