Detailed information of TA system TA026226

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3345757..3346369
• Replicon: chromosome
• Accession: NC_017052
• Organism: Synechocystis sp. PCC 6803 substr. PCC-N

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SYNPCCN_RS15520
• Protein ID: WP_010874170.1
• Coordinates: 3346007..3346369 (+)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SYNPCCN_RS15515
• Protein ID: WP_010874169.1
• Coordinates: 3345757..3346017 (+)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SYNPCCN_RS15500	3342843..3343631	-	789	WP_010874166.1	hypothetical protein	-
SYNPCCN_RS15505	3343677..3344633	-	957	WP_010874167.1	quinolinate synthase NadA	-
SYNPCCN_RS15510	3344726..3345472	-	747	WP_010874168.1	cytochrome c biogenesis protein CcdA	-
SYNPCCN_RS15515	3345757..3346017	+	261	WP_010874169.1	hypothetical protein	Antitoxin
SYNPCCN_RS15520	3346007..3346369	+	363	WP_010874170.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SYNPCCN_RS15525	3346506..3349112	+	2607	WP_010874171.1	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	-
SYNPCCN_RS15530	3349342..3350169	+	828	WP_010874172.1	hypothetical protein	-
SYNPCCN_RS15535	3350498..3351019	+	522	WP_010874173.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (37-110)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13679.59 Da
• Isoelectric Point: 8.2767

>T26226 WP_010874170.1 NC_017052:3346007-3346369 [Synechocystis sp. PCC 6803 substr. PCC-N]
MSNNLHLVNIDFTPEYRRSLKYLAKKYRNIRSDVQPIIEALQKGVISGDRLAGFGSDIYVYKLRIKNSNIQKGKSSGYRL
IYLLESENSILLLTIYSKAEQEDIAASDINSILGEYSIED

Nucleotide

• Length: 363 bp

>T26226 NC_017052:3346007-3346369 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGTCGAATAATCTCCATTTAGTCAATATCGACTTCACCCCCGAATATAGGAGAAGTTTAAAATATTTAGCCAAGAAATA
TCGAAATATTCGTTCTGATGTTCAGCCCATTATTGAGGCTTTGCAAAAAGGCGTCATTAGTGGTGATCGCCTGGCAGGGT
TTGGCTCTGATATTTACGTCTATAAGCTTAGAATTAAGAATAGTAATATTCAGAAAGGGAAAAGTTCTGGCTACCGATTA
ATTTATTTACTCGAATCAGAAAACAGTATTTTGTTGTTAACCATTTACAGTAAAGCTGAACAAGAAGATATTGCCGCTAG
TGACATTAATTCAATTTTAGGGGAGTACTCCATAGAAGACTAA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9909.29 Da
• Isoelectric Point: 4.3705

>AT26226 WP_010874169.1 NC_017052:3345757-3346017 [Synechocystis sp. PCC 6803 substr. PCC-N]
MMRAFEVMATVKDSKQLLLDSDLHWNTSRVKVIILESDELASKGSEFDPDDTPVEEIKVSLRKALEEYKQGKRIPVENMW
EGIDVE

Nucleotide

• Length: 261 bp

>AT26226 NC_017052:3345757-3346017 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGATGAGAGCTTTTGAGGTAATGGCCACAGTTAAAGATTCCAAACAATTGCTCTTGGATAGTGATTTGCATTGGAATAC
CAGCCGAGTCAAGGTGATTATTTTGGAATCAGATGAATTGGCATCAAAAGGAAGTGAGTTTGATCCTGATGACACGCCTG
TCGAAGAAATTAAGGTGAGTTTGAGGAAGGCATTAGAGGAATATAAACAAGGAAAAAGAATTCCAGTAGAAAATATGTGG
GAGGGAATTGATGTCGAATAA