Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2083641..2084026 Replicon chromosome
Accession NC_017052
Organism Synechocystis sp. PCC 6803 substr. PCC-N

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag SYNPCCN_RS16905 Protein ID WP_080504056.1
Coordinates 2083922..2084026 (+) Length 35 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag SYNPCCN_RS09890 Protein ID WP_010873096.1
Coordinates 2083641..2083925 (+) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCN_RS09855 2078700..2080535 + 1836 WP_010873091.1 hypothetical protein -
SYNPCCN_RS09860 2080679..2081731 - 1053 WP_010873092.1 2OG-Fe(II) oxygenase -
SYNPCCN_RS09865 2081958..2082185 + 228 WP_020862282.1 DUF2281 domain-containing protein -
SYNPCCN_RS16900 2082231..2082575 + 345 WP_071822655.1 type II toxin-antitoxin system VapC family toxin -
SYNPCCN_RS09875 2082737..2083021 + 285 WP_014407120.1 BrnT family toxin -
SYNPCCN_RS09880 2083026..2083232 + 207 WP_010873094.1 hypothetical protein -
SYNPCCN_RS09885 2083260..2083499 + 240 WP_010873095.1 hypothetical protein -
SYNPCCN_RS09890 2083641..2083925 + 285 WP_010873096.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
SYNPCCN_RS16905 2083922..2084026 + 105 WP_080504056.1 type II toxin-antitoxin system YoeB family toxin Toxin
SYNPCCN_RS09895 2084120..2084944 - 825 WP_010873097.1 photosystem II manganese-stabilizing polypeptide -
SYNPCCN_RS09900 2085171..2085548 + 378 WP_010873098.1 hypothetical protein -
SYNPCCN_RS09910 2085945..2086307 - 363 WP_010873099.1 hypothetical protein -
SYNPCCN_RS09915 2086495..2087838 + 1344 WP_010873100.1 3-phosphoshikimate 1-carboxyvinyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-32)

Antitoxin

(19-83)


Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 4196.90 Da        Isoelectric Point: 8.5633

>T26223 WP_080504056.1 NC_017052:2083922-2084026 [Synechocystis sp. PCC 6803 substr. PCC-N]
VKLIFSEQAWSDYLYWQQNDKKILKRINTLVELI

Download         Length: 105 bp

>T26223 NC_017052:2083922-2084026 [Synechocystis sp. PCC 6803 substr. PCC-N]
GTGAAGCTAATTTTCTCTGAGCAAGCCTGGAGCGATTATCTTTACTGGCAACAAAACGACAAGAAAATACTTAAAAGAAT
CAATACCTTAGTTGAATTAATTTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10540.02 Da        Isoelectric Point: 4.1364

>AT26223 WP_010873096.1 NC_017052:2083641-2083925 [Synechocystis sp. PCC 6803 substr. PCC-N]
MGETLPQQLPNMNAVSQIIAQQKLAAIMEQVCSDHVPTIITRDTQPSVVMISLEDYQSLEETAYLLRSPNNAQKLMSAIK
QLENDQGVERELLE

Download         Length: 285 bp

>AT26223 NC_017052:2083641-2083925 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGGGGGAAACTTTGCCCCAACAATTGCCAAACATGAACGCAGTCAGCCAAATTATTGCACAACAAAAACTTGCAGCTAT
CATGGAGCAAGTATGTAGTGATCATGTTCCAACAATTATCACCAGGGATACCCAACCATCTGTCGTCATGATTTCCCTGG
AAGACTATCAGTCATTAGAAGAAACAGCATATCTACTACGTAGCCCGAACAATGCTCAAAAATTGATGTCGGCGATCAAG
CAATTAGAAAATGATCAAGGTGTCGAAAGGGAACTATTGGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References