Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 508006..508708 Replicon plasmid pESL4.1
Accession NZ_CP109854
Organism Pantoea dispersa strain ESL4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OH655_RS21410 Protein ID WP_264444068.1
Coordinates 508325..508708 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A246NDH1
Locus tag OH655_RS21405 Protein ID WP_058770279.1
Coordinates 508006..508332 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH655_RS21385 (OH655_21385) 503634..504668 - 1035 WP_264444060.1 aldehyde reductase -
OH655_RS21390 (OH655_21390) 504777..505709 + 933 WP_264444062.1 AraC family transcriptional regulator -
OH655_RS21395 (OH655_21395) 505737..506771 - 1035 WP_058770277.1 L-glyceraldehyde 3-phosphate reductase -
OH655_RS21400 (OH655_21400) 506941..507840 + 900 WP_264444064.1 LysR family transcriptional regulator -
OH655_RS21405 (OH655_21405) 508006..508332 - 327 WP_058770279.1 helix-turn-helix domain-containing protein Antitoxin
OH655_RS21410 (OH655_21410) 508325..508708 - 384 WP_264444068.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH655_RS21415 (OH655_21415) 509013..509303 + 291 WP_021508990.1 hypothetical protein -
OH655_RS21420 (OH655_21420) 509328..510755 - 1428 WP_264444072.1 trehalose-6-phosphate synthase -
OH655_RS21425 (OH655_21425) 510928..511791 - 864 WP_264444075.1 substrate-binding domain-containing protein -
OH655_RS21430 (OH655_21430) 512023..512718 + 696 WP_058775966.1 hypothetical protein -
OH655_RS21435 (OH655_21435) 512816..513346 + 531 WP_264444078.1 outer membrane lipoprotein Blc -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..690879 690879


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-123)

Antitoxin

Cro/C1-type helix-turn-helix domain

(53-95)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14083.43 Da        Isoelectric Point: 10.2744

>T262228 WP_264444068.1 NZ_CP109854:c508708-508325 [Pantoea dispersa]
MAIYVLKPFDRNFKGDMIADIKLCLAARELIAGQYEASLGGGVYKKRIPLGAGKSGGARAIVAFKSQKHLFFVNGYAKST
TKSGIREIKEDEINFYRQVASQLFAMTTEQERAAIKARKMREVICDG

Download         Length: 384 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12292.30 Da        Isoelectric Point: 7.3214

>AT262228 WP_058770279.1 NZ_CP109854:c508332-508006 [Pantoea dispersa]
MVDHLKDLQEIAHDFNPLGVISDELTEKIDSRVRLRELRTSLPVLQLMSGEAIRELRERHGLSQAMLAAYIGLSPATVVK
WEREEKKPNGAALRLLNLIDRKGLEVLR

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A246NDH1

References