262226

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 279817..280352 Replicon plasmid pESL4.1
Accession NZ_CP109854
Organism Pantoea dispersa strain ESL4

Toxin (Protein)


Gene name relE Uniprot ID A0A246NE43
Locus tag OH655_RS20405 Protein ID WP_058770149.1
Coordinates 279817..280104 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OH655_RS20410 Protein ID WP_058770150.1
Coordinates 280101..280352 (-) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH655_RS20385 (OH655_20385) 275563..276534 + 972 WP_058758760.1 autoinducer 2 ABC transporter substrate-binding protein -
OH655_RS20390 (OH655_20390) 276546..277487 + 942 WP_264444630.1 ABC transporter permease -
OH655_RS20395 (OH655_20395) 277484..278428 + 945 WP_021509450.1 ABC transporter permease -
OH655_RS20400 (OH655_20400) 278432..279766 + 1335 WP_058758757.1 ArgE/DapE family deacylase -
OH655_RS20405 (OH655_20405) 279817..280104 - 288 WP_058770149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OH655_RS20410 (OH655_20410) 280101..280352 - 252 WP_058770150.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OH655_RS20415 (OH655_20415) 280484..282673 - 2190 WP_264444635.1 aldehyde oxidoreductase molybdenum-binding subunit PaoC -
OH655_RS20420 (OH655_20420) 282670..283626 - 957 WP_264444637.1 xanthine dehydrogenase family protein subunit M -
OH655_RS20425 (OH655_20425) 283623..284243 - 621 WP_104187284.1 aldehyde dehydrogenase iron-sulfur subunit PaoA -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..690879 690879


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-83)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 96 a.a.        Molecular weight: 11155.16 Da        Isoelectric Point: 10.4346

>T262226 WP_058770149.1 NZ_CP109854:c280104-279817 [Pantoea dispersa]
VTWTVKFREEALKEWHKLDKAIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRASGFRLVYQVIDDQLIIAVVAVGK
RERSDVYHLASDRMR

Download         Length: 288 bp


Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9270.67 Da        Isoelectric Point: 4.1947

>AT262226 WP_058770150.1 NZ_CP109854:c280352-280101 [Pantoea dispersa]
MPNIILSDMSASVSELKKNPMATVNAGEGLPVAILNRNQPAFYCVPAQLYEQMLEALDDQELVKKVTERHQQPLIEVDLD
SFL

Download         Length: 252 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A246NE43


Antitoxin

Source ID Structure

References