Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3703495..3704399 Replicon chromosome
Accession NZ_CP109853
Organism Pantoea dispersa strain ESL4

Toxin (Protein)


Gene name - Uniprot ID A0A8E1V7L7
Locus tag OH655_RS17225 Protein ID WP_058774932.1
Coordinates 3703935..3704399 (+) Length 155 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A246NMT1
Locus tag OH655_RS17220 Protein ID WP_058757556.1
Coordinates 3703495..3703938 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH655_RS17200 (OH655_17200) 3699606..3700001 + 396 WP_031279757.1 transposase -
OH655_RS17205 (OH655_17205) 3700911..3701864 - 954 WP_104093916.1 DMT family transporter -
OH655_RS17210 (OH655_17210) 3701937..3702767 - 831 WP_058757554.1 AraC family transcriptional regulator -
OH655_RS17215 (OH655_17215) 3702894..3703421 + 528 WP_264441737.1 isochorismatase family protein -
OH655_RS17220 (OH655_17220) 3703495..3703938 + 444 WP_058757556.1 DUF2384 domain-containing protein Antitoxin
OH655_RS17225 (OH655_17225) 3703935..3704399 + 465 WP_058774932.1 RES domain-containing protein Toxin
OH655_RS17230 (OH655_17230) 3704451..3704993 - 543 WP_021507842.1 single-stranded DNA-binding protein SSB1 -
OH655_RS17235 (OH655_17235) 3705215..3708043 + 2829 WP_021507843.1 excinuclease ABC subunit UvrA -
OH655_RS17240 (OH655_17240) 3708319..3709383 + 1065 WP_058780888.1 NAD(P)-dependent alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 155 a.a.        Molecular weight: 17117.59 Da        Isoelectric Point: 5.1259

>T262224 WP_058774932.1 NZ_CP109853:3703935-3704399 [Pantoea dispersa]
VIFYRLTKSQYAAEAWSGYGAKQYGGRWNHKGYPTVYVATSVSLAALEVLVHIGRESVLDEYTLFSIDIPDAEVAYLAEA
FLPPDWRHDPAPLSTMDLGTGWLQSAEGAALMLPSTIIPMENNAILNPLHPAFSDYLPGVKALPFMFDRRLIRT

Download         Length: 465 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16114.59 Da        Isoelectric Point: 9.9132

>AT262224 WP_058757556.1 NZ_CP109853:3703495-3703938 [Pantoea dispersa]
MRAYIPQPGANDNALWRVAGLPPRGIELTRMLEAGLPVAVIDDIRHWSAMTRAEIMKVTGINERNIARRKSTGKSLSPDE
SERVARFVRVMDAAVQLFAGNKEEATQWLSRPVKGLGNVAPITLLTTESGALDVLDLIGRLEHGVFS

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A246NMT1

References