Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1932484..1933076 Replicon chromosome
Accession NC_017052
Organism Synechocystis sp. PCC 6803 substr. PCC-N

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SYNPCCN_RS09175 Protein ID WP_010872957.1
Coordinates 1932484..1932870 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SYNPCCN_RS09180 Protein ID WP_010872958.1
Coordinates 1932870..1933076 (-) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCN_RS09165 1930155..1931327 + 1173 WP_010872955.1 sulfate adenylyltransferase -
SYNPCCN_RS09170 1931370..1932434 + 1065 WP_010872956.1 glycosyltransferase -
SYNPCCN_RS09175 1932484..1932870 - 387 WP_010872957.1 type II toxin-antitoxin system VapC family toxin Toxin
SYNPCCN_RS09180 1932870..1933076 - 207 WP_010872958.1 DUF2281 domain-containing protein Antitoxin
SYNPCCN_RS09185 1933323..1934546 - 1224 WP_010872959.1 geranylgeranyl reductase -
SYNPCCN_RS09190 1934928..1936085 + 1158 WP_010872960.1 oxidoreductase -
SYNPCCN_RS09195 1936102..1936413 + 312 WP_010872961.1 DUF433 domain-containing protein -
SYNPCCN_RS09200 1936490..1937326 + 837 WP_010872962.1 DUF1049 domain-containing protein -
SYNPCCN_RS09205 1937445..1937798 + 354 WP_010872963.1 TMEM165/GDT1 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(5-127)

Antitoxin

Domain of unknown function DUF2281

(7-67)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14814.14 Da        Isoelectric Point: 6.0713

>T26222 WP_010872957.1 NC_017052:c1932870-1932484 [Synechocystis sp. PCC 6803 substr. PCC-N]
MNSVLIDTHVFIWLAEDDSNLPVTTKDTLENMDNVFVSIASFWEISIKLKIGKLSLCGDFNSIEASFQRTRFKLLPITLK
DTIKLYNLPLHHKDPFDRILVSQSINHSLILVSRDQALDDYPIQRLWL

Download         Length: 387 bp

>T26222 NC_017052:c1932870-1932484 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGAATTCTGTTTTGATAGACACCCACGTTTTTATTTGGTTAGCAGAAGATGACTCTAACTTGCCTGTGACGACAAAAGA
TACCTTAGAAAATATGGATAACGTTTTTGTTAGTATTGCCAGCTTTTGGGAAATTTCTATTAAACTAAAAATTGGTAAAC
TTTCTCTCTGTGGTGATTTCAATAGTATTGAAGCTAGTTTTCAAAGAACCCGATTCAAGCTATTACCTATTACACTAAAA
GACACAATTAAACTTTATAATCTTCCCTTGCACCACAAAGATCCCTTTGATCGTATTTTGGTATCCCAATCGATTAATCA
TTCTCTTATTTTAGTCAGTCGTGATCAAGCTCTGGATGATTATCCGATTCAACGCCTGTGGTTGTAG

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7699.84 Da        Isoelectric Point: 3.8804

>AT26222 WP_010872958.1 NC_017052:c1933076-1932870 [Synechocystis sp. PCC 6803 substr. PCC-N]
MTTEAALLNIAENLPDDLKIELLHYAEYLMNKSLNAPQKPLAGSMKGTFILPLPEDFDAPLEEFEEYM

Download         Length: 207 bp

>AT26222 NC_017052:c1933076-1932870 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGACTACTGAAGCTGCCCTATTAAACATTGCTGAAAATCTGCCTGATGACTTAAAAATCGAGCTTTTACACTATGCTGA
ATATTTAATGAATAAATCCTTAAATGCGCCCCAAAAGCCATTAGCAGGATCGATGAAAGGAACTTTTATTTTACCTCTAC
CCGAAGACTTTGATGCCCCCTTAGAAGAATTTGAGGAGTATATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References