Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1659085..1659727 Replicon chromosome
Accession NC_017052
Organism Synechocystis sp. PCC 6803 substr. PCC-N

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SYNPCCN_RS07830 Protein ID WP_010872706.1
Coordinates 1659293..1659727 (+) Length 145 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SYNPCCN_RS07825 Protein ID WP_010872705.1
Coordinates 1659085..1659303 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCN_RS07810 1654305..1654688 - 384 WP_010872702.1 heterocyst frequency control protein PatD -
SYNPCCN_RS07815 1655059..1657341 + 2283 WP_010872703.1 RelA/SpoT family protein -
SYNPCCN_RS07820 1657527..1658804 - 1278 WP_010872704.1 adenosylhomocysteinase -
SYNPCCN_RS07825 1659085..1659303 + 219 WP_010872705.1 hypothetical protein Antitoxin
SYNPCCN_RS07830 1659293..1659727 + 435 WP_010872706.1 putative toxin-antitoxin system toxin component, PIN family Toxin
SYNPCCN_RS07835 1659755..1660639 - 885 WP_010872707.1 transglutaminase family protein -
SYNPCCN_RS07840 1660738..1661301 - 564 WP_010872708.1 Uma2 family endonuclease -
SYNPCCN_RS07845 1661322..1662521 - 1200 WP_010872709.1 glycosyltransferase family 4 protein -
SYNPCCN_RS07850 1662570..1663706 - 1137 WP_010872710.1 hybrid sensor histidine kinase/response regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 145 a.a.        Molecular weight: 16459.94 Da        Isoelectric Point: 4.4099

>T26221 WP_010872706.1 NC_017052:1659293-1659727 [Synechocystis sp. PCC 6803 substr. PCC-N]
MNNEVIRVVIDTNIWISFLIGKTLQGLNQAIIDNQVVILFSDTLFTELMEVLHHPKFKKYFSGTAIQNLIALLNEKVELV
EVNLHFDSYRDKKDNFLLDLAVSGNANYLVTGDSDLLTLNPFDNVEIISYQHFQAIILAMMDNQ

Download         Length: 435 bp

>T26221 NC_017052:1659293-1659727 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGAACAATGAAGTTATCCGGGTTGTAATTGATACGAATATCTGGATCAGTTTTCTAATTGGAAAAACTCTTCAAGGTTT
AAATCAAGCCATCATTGATAACCAAGTGGTCATTTTATTCAGTGACACTTTGTTTACTGAGCTGATGGAAGTATTACACC
ATCCTAAATTCAAAAAGTACTTTTCCGGAACAGCCATCCAAAATTTAATCGCACTGTTAAACGAAAAAGTTGAATTGGTT
GAAGTGAATCTTCATTTTGACAGTTATCGAGACAAAAAAGATAATTTCTTGCTGGATTTGGCAGTCTCAGGCAATGCAAA
TTATTTGGTGACGGGAGATAGTGACCTATTGACATTAAACCCATTTGACAATGTAGAAATTATCTCCTATCAACATTTTC
AAGCTATTATTTTAGCCATGATGGATAATCAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8400.43 Da        Isoelectric Point: 4.2583

>AT26221 WP_010872705.1 NC_017052:1659085-1659303 [Synechocystis sp. PCC 6803 substr. PCC-N]
MHSLSSLEFPELKSVIAQCNLEEKLELLELLEKDTFGTRFNKFLNSVKTDELTLEDITQEVESVRQANYHEQ

Download         Length: 219 bp

>AT26221 NC_017052:1659085-1659303 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGCACTCATTGTCATCACTGGAATTTCCTGAGCTTAAAAGTGTTATTGCCCAATGTAATCTTGAAGAAAAACTTGAATT
ATTAGAACTTTTGGAAAAGGATACTTTTGGCACCAGATTTAACAAATTTTTAAATTCTGTCAAAACTGACGAATTAACCT
TAGAAGACATTACACAAGAAGTTGAATCGGTCCGGCAAGCTAATTATCATGAACAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References