Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4868019..4869277 | Replicon | chromosome |
Accession | NZ_CP109849 | ||
Organism | Pseudomonas aeruginosa strain PALA34 |
Toxin (Protein)
Gene name | - | Uniprot ID | Q9I4U4 |
Locus tag | PALA34_RS22710 | Protein ID | WP_003112528.1 |
Coordinates | 4868019..4868774 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PALA34_RS22715 | Protein ID | WP_003086329.1 |
Coordinates | 4868909..4869277 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA34_RS22700 (PALA34_04492) | 4863192..4865735 | + | 2544 | WP_003112526.1 | acyl-homoserine-lactone acylase QuiP | - |
PALA34_RS22705 (PALA34_04493) | 4865890..4867251 | - | 1362 | WP_073647918.1 | DNA recombination protein RmuC | - |
PALA34_RS22710 (PALA34_04494) | 4868019..4868774 | - | 756 | WP_003112528.1 | RES family NAD+ phosphorylase | Toxin |
PALA34_RS22715 (PALA34_04495) | 4868909..4869277 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PALA34_RS22720 (PALA34_04496) | 4869350..4870636 | - | 1287 | WP_003112529.1 | FAD-binding oxidoreductase | - |
PALA34_RS22725 (PALA34_04497) | 4870692..4872281 | - | 1590 | WP_003125055.1 | aldehyde dehydrogenase family protein | - |
PALA34_RS22730 (PALA34_04498) | 4872360..4872836 | + | 477 | WP_003112531.1 | hypothetical protein | - |
PALA34_RS22735 | 4872839..4873114 | - | 276 | WP_169057979.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28278.42 Da Isoelectric Point: 7.7294
>T262201 WP_003112528.1 NZ_CP109849:c4868774-4868019 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMVVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT262201 WP_003086329.1 NZ_CP109849:c4869277-4868909 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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