Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 545119..545678 Replicon chromosome
Accession NC_017052
Organism Synechocystis sp. PCC 6803 substr. PCC-N

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SYNPCCN_RS02525 Protein ID WP_010871694.1
Coordinates 545340..545678 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SYNPCCN_RS02520 Protein ID WP_010871693.1
Coordinates 545119..545343 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCN_RS02495 540152..540853 + 702 WP_071822669.1 HAD family hydrolase -
SYNPCCN_RS02500 540953..542155 + 1203 WP_010871689.1 class I SAM-dependent methyltransferase -
SYNPCCN_RS02505 542195..542686 - 492 WP_010871690.1 hypothetical protein -
SYNPCCN_RS02510 542893..543432 + 540 WP_010871691.1 tellurium resistance TerZ family protein -
SYNPCCN_RS02515 543558..544961 - 1404 WP_010871692.1 glutamate decarboxylase -
SYNPCCN_RS02520 545119..545343 + 225 WP_010871693.1 DUF433 domain-containing protein Antitoxin
SYNPCCN_RS02525 545340..545678 + 339 WP_010871694.1 DUF5615 family PIN-like protein Toxin
SYNPCCN_RS02530 545681..546646 - 966 WP_010871695.1 carbon-nitrogen hydrolase family protein -
SYNPCCN_RS02535 546643..547455 - 813 WP_014407074.1 urease accessory protein UreD -
SYNPCCN_RS02540 547515..547964 - 450 WP_010871697.1 photosystem II protein PsbQ -
SYNPCCN_RS02545 548326..549222 + 897 WP_010871698.1 prohibitin family protein -
SYNPCCN_RS02550 549219..549791 - 573 WP_010871699.1 gamma carbonic anhydrase family protein -
SYNPCCN_RS02555 550084..550419 + 336 WP_010871700.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-78)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12464.32 Da        Isoelectric Point: 4.2931

>T26220 WP_010871694.1 NC_017052:545340-545678 [Synechocystis sp. PCC 6803 substr. PCC-N]
MNIWVDAQLPPTLADWLSSNFDLEASALRDLGLRDARDIEIFDAARVANSVIMTKDSDFVDLVCRLGIPPQIIWLTCGNV
TNRNLRRILSSTLPQALEKLQAGEIIIEISNS

Download         Length: 339 bp

>T26220 NC_017052:545340-545678 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGAATATTTGGGTTGATGCTCAACTACCTCCAACATTGGCAGATTGGCTGTCGAGTAATTTTGATTTAGAGGCGTCAGC
TTTGAGGGATCTGGGATTACGGGATGCAAGAGACATTGAAATTTTTGATGCCGCACGAGTTGCCAACTCTGTAATCATGA
CAAAAGACAGCGACTTCGTTGATCTTGTATGTCGATTAGGAATACCACCTCAAATCATTTGGCTAACTTGCGGTAACGTT
ACGAATCGAAACTTACGTCGAATTCTCTCAAGTACTTTGCCACAGGCTCTGGAAAAACTGCAAGCAGGCGAAATTATCAT
AGAAATCAGCAACTCCTGA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8232.51 Da        Isoelectric Point: 4.6320

>AT26220 WP_010871693.1 NC_017052:545119-545343 [Synechocystis sp. PCC 6803 substr. PCC-N]
MNSLLSRITQTPGQCGGRPCIRGMRIRVSDILEMLAENVSTSEILEDFPDLEMADIQACLVFAARRTDFSRLTA

Download         Length: 225 bp

>AT26220 NC_017052:545119-545343 [Synechocystis sp. PCC 6803 substr. PCC-N]
ATGAATAGCTTACTGTCTCGCATTACCCAAACCCCCGGTCAGTGTGGTGGTCGTCCTTGTATTCGAGGGATGAGGATTCG
AGTGAGCGACATCCTAGAAATGTTAGCTGAGAATGTTAGCACCTCTGAGATTTTAGAGGACTTTCCAGACCTAGAAATGG
CCGATATTCAGGCTTGTCTAGTGTTTGCTGCACGGCGGACTGATTTTTCCCGGTTGACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References