Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3071455..3071963 Replicon chromosome
Accession NZ_CP109846
Organism Providencia rettgeri strain 12105 isolate P12105

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NTP67_RS14090 Protein ID WP_129465771.1
Coordinates 3071655..3071963 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag NTP67_RS14085 Protein ID WP_238563506.1
Coordinates 3071455..3071655 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NTP67_RS14065 (NTP67_14065) 3066884..3067186 + 303 WP_042844270.1 flagellar biosynthesis anti-sigma factor FlgM -
NTP67_RS14070 (NTP67_14070) 3067196..3067636 + 441 WP_042844271.1 flagellar export chaperone FlgN -
NTP67_RS14075 (NTP67_14075) 3068007..3070106 - 2100 WP_042844272.1 flagellar biosynthesis protein FlhA -
NTP67_RS14080 (NTP67_14080) 3070099..3071250 - 1152 WP_042844273.1 flagellar biosynthesis protein FlhB -
NTP67_RS14085 (NTP67_14085) 3071455..3071655 + 201 WP_238563506.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NTP67_RS14090 (NTP67_14090) 3071655..3071963 + 309 WP_129465771.1 CcdB family protein Toxin
NTP67_RS14095 (NTP67_14095) 3071979..3072536 + 558 WP_129465770.1 hypothetical protein -
NTP67_RS14100 (NTP67_14100) 3072557..3072856 - 300 WP_042844276.1 helix-turn-helix transcriptional regulator -
NTP67_RS14105 (NTP67_14105) 3073073..3073711 - 639 WP_042844277.1 protein phosphatase CheZ -
NTP67_RS14110 (NTP67_14110) 3073736..3074128 - 393 WP_034782834.1 chemotaxis response regulator CheY -
NTP67_RS14115 (NTP67_14115) 3074168..3075235 - 1068 WP_042844278.1 chemotaxis response regulator protein-glutamate methylesterase -
NTP67_RS14120 (NTP67_14120) 3075235..3076071 - 837 WP_042844279.1 CheR family methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(1-66)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11649.69 Da        Isoelectric Point: 6.4602

>T262196 WP_129465771.1 NZ_CP109846:3071655-3071963 [Providencia rettgeri]
MQYCLYQNREDTVKHPYLLDIQSNIIDILNTLLVIPLFDSRLAKKPLPTCLNPQLFSNGQVFVLMTHQMACVPHSLLGKE
IVDLNCQQNTIKHAIDLLIDGF

Download         Length: 309 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7596.66 Da        Isoelectric Point: 7.7889

>AT262196 WP_238563506.1 NZ_CP109846:3071455-3071655 [Providencia rettgeri]
ITVAPELCEQARRAKLNLSAILTCALQAELKRLEAQKWKNENIEGFNQLNRNNEEYGLLSDKYKGF

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References