Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-TIGR02293 |
| Location | 2573907..2574826 | Replicon | chromosome |
| Accession | NZ_CP109846 | ||
| Organism | Providencia rettgeri strain 12105 isolate P12105 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A1J0E7D4 |
| Locus tag | NTP67_RS11730 | Protein ID | WP_042843809.1 |
| Coordinates | 2574365..2574826 (+) | Length | 154 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | NTP67_RS11725 | Protein ID | WP_048607179.1 |
| Coordinates | 2573907..2574368 (+) | Length | 154 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NTP67_RS11690 (NTP67_11690) | 2569013..2569477 | - | 465 | WP_221078262.1 | NUDIX domain-containing protein | - |
| NTP67_RS11695 (NTP67_11695) | 2569501..2569887 | - | 387 | WP_042843801.1 | cytidine deaminase | - |
| NTP67_RS11700 (NTP67_11700) | 2570306..2570764 | + | 459 | WP_042843802.1 | GNAT family N-acetyltransferase | - |
| NTP67_RS11705 (NTP67_11705) | 2570824..2571465 | - | 642 | WP_048607183.1 | leucine efflux protein LeuE | - |
| NTP67_RS11710 (NTP67_11710) | 2572152..2572853 | + | 702 | WP_048607181.1 | AzlC family ABC transporter permease | - |
| NTP67_RS11715 (NTP67_11715) | 2572850..2573164 | + | 315 | WP_042843806.1 | AzlD domain-containing protein | - |
| NTP67_RS11720 (NTP67_11720) | 2573350..2573817 | + | 468 | WP_042843807.1 | DUF1456 family protein | - |
| NTP67_RS11725 (NTP67_11725) | 2573907..2574368 | + | 462 | WP_048607179.1 | DUF2384 domain-containing protein | Antitoxin |
| NTP67_RS11730 (NTP67_11730) | 2574365..2574826 | + | 462 | WP_042843809.1 | RES domain-containing protein | Toxin |
| NTP67_RS11735 (NTP67_11735) | 2574835..2575725 | - | 891 | WP_131680005.1 | LysR family transcriptional regulator | - |
| NTP67_RS11740 (NTP67_11740) | 2575769..2576728 | - | 960 | WP_206226925.1 | acetyl-CoA carboxylase carboxyl transferase subunit alpha | - |
| NTP67_RS11745 (NTP67_11745) | 2576835..2577257 | - | 423 | WP_042843814.1 | helix-turn-helix domain-containing protein | - |
| NTP67_RS11750 (NTP67_11750) | 2577314..2577847 | - | 534 | WP_226619150.1 | GNAT family N-acetyltransferase | - |
| NTP67_RS11755 (NTP67_11755) | 2577864..2579324 | - | 1461 | WP_042844339.1 | AMP nucleosidase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 154 a.a. Molecular weight: 17499.99 Da Isoelectric Point: 6.4846
>T262195 WP_042843809.1 NZ_CP109846:2574365-2574826 [Providencia rettgeri]
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
MILYRLIKSDFAHDAWSGQGARLYGGRWNHKGTPAIYTSTSISLAALEILVHINQDTVLNHFTLLSIEINDRYVMKLSVE
HLPDDWQRDPAPTSTMDIGTTWLTNQDSLALIVPSCIIPYEYNAIINPMHPQFQKVTQTIKPLDFAFDPRFNR
Download Length: 462 bp
Antitoxin
Download Length: 154 a.a. Molecular weight: 17056.55 Da Isoelectric Point: 9.9812
>AT262195 WP_048607179.1 NZ_CP109846:2573907-2574368 [Providencia rettgeri]
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
MRNYIPALPTQPATPPFKPLWRFAGLPAERGIELTHFLRQGLSVTVLDNIQEWSGISKSELLRISGINERNVARRRNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKSMASDWLNHPVKGLGHTRPIELIATESGALEVIDLIGRIEHGVFS
Download Length: 462 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|