Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3667038..3667655 Replicon chromosome
Accession NC_017047
Organism Rahnella aquatilis HX2

Toxin (Protein)


Gene name Hha Uniprot ID H8NYI7
Locus tag Q7S_RS16635 Protein ID WP_013576617.1
Coordinates 3667452..3667655 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID H8NYI6
Locus tag Q7S_RS16630 Protein ID WP_013576616.1
Coordinates 3667038..3667406 (+) Length 123 a.a.

Genomic Context

Q7S_RS16600Q7S_RS16605Q7S_RS16625Q7S_RS16630Q7S_RS16635Q7S_RS16645Q7S_RS16650Q7S_RS16610Q7S_RS16615Q7S_RS16620Q7S_RS16640
Location: 3663028..3663282 (255 bp)
Type: Others
Protein ID: WP_013576610.1
Location: 3663303..3663443 (141 bp)
Type: Others
Protein ID: WP_013576611.1
Location: 3666455..3666808 (354 bp)
Type: Others
Protein ID: WP_013576615.1
Location: 3667038..3667406 (369 bp)
Type: Antitoxin
Protein ID: WP_013576616.1
Location: 3667452..3667655 (204 bp)
Type: Toxin
Protein ID: WP_013576617.1
Location: 3668827..3670614 (1788 bp)
Type: Others
Protein ID: WP_013576619.1
Location: 3670691..3672040 (1350 bp)
Type: Others
Protein ID: WP_013576620.1
Location: 3663568..3664446 (879 bp)
Type: Others
Protein ID: WP_013576612.1
Location: 3664490..3665347 (858 bp)
Type: Others
Protein ID: WP_013576613.1
Location: 3665344..3666072 (729 bp)
Type: Others
Protein ID: WP_173362112.1
Location: 3667731..3668687 (957 bp)
Type: Others
Protein ID: WP_013576618.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
Q7S_RS166003663028..3663282+255WP_013576610.1type B 50S ribosomal protein L31-
Q7S_RS166053663303..3663443+141WP_013576611.1type B 50S ribosomal protein L36-
Q7S_RS166103663568..3664446-879WP_013576612.1metal ABC transporter substrate-binding protein-
Q7S_RS166153664490..3665347-858WP_013576613.1metal ABC transporter permease-
Q7S_RS166203665344..3666072-729WP_173362112.1ABC transporter ATP-binding protein-
Q7S_RS166253666455..3666808+354WP_013576615.1hypothetical protein-
Q7S_RS166303667038..3667406+369WP_013576616.1Hha toxicity modulator TomBAntitoxin
Q7S_RS166353667452..3667655+204WP_013576617.1hemolysin expression modulator HhaToxin
Q7S_RS166403667731..3668687-957WP_013576618.1LysR family transcriptional regulator-
Q7S_RS166453668827..3670614+1788WP_013576619.1adenine deaminase-
Q7S_RS166503670691..3672040+1350WP_013576620.1NCS2 family permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8114.45 Da        Isoelectric Point: 6.9764

>T26218 WP_013576617.1 NC_017047:3667452-3667655 [Rahnella aquatilis HX2]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVSVWKFVR

Download         Length: 204 bp

>T26218 NC_017047:3667452-3667655 [Rahnella aquatilis HX2]
ATGAACAAAATCGACTATTTGATGCGTTTACGAAAATGCACCACTATCGATACACTTGAACGTGTTATTGAAAAAAATAA
GTACGAACTTTCCGACGACGAGCTGGAATTGTTTTACTCGGCAGCTGACCATCGTTTAGCGGAGCTAACGATGAACAAGT
TGTACGATAAAATCCCGGTATCAGTCTGGAAATTTGTACGCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14391.15 Da        Isoelectric Point: 4.7281

>AT26218 WP_013576616.1 NC_017047:3667038-3667406 [Rahnella aquatilis HX2]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKYPDDNHLSDLVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp

>AT26218 NC_017047:3667038-3667406 [Rahnella aquatilis HX2]
ATGGATGAGTACTCGCCTAAGCGGCACGATATCGCTCAGTTACGCTACCTGAATGAAATGCTGTATGATGAAGGGATTGC
GACACTGGGTGACAGTCATCATGGTTGGGTTAACGATCCGACTTCGGCTGTTAACTTGCAGCTCAATGAACTGATTGAGC
ACATTGCATCCTTTGTGATGAGTTTTAAAATTAAGTATCCAGACGATAACCATTTAAGTGATCTGGTTGAAGAGTATCTG
GATGATACCTACACGCTGTTCAGTAATTATGGAATTAACGATTCTGATTTACGCCAATGGCAAAAGACCAAGAAGCGGTT
ATTCAGAATGTTCTCAGGGGACTACATCTGTACCCTAATGAAGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH8NYI7

Antitoxin

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Source
ID
Structure
AlphaFold DBH8NYI6

References