Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3636174..3636827 Replicon chromosome
Accession NZ_CP109836
Organism Acinetobacter baumannii strain Z198

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OHJ24_RS17615 Protein ID WP_000607077.1
Coordinates 3636174..3636563 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag OHJ24_RS17620 Protein ID WP_001288210.1
Coordinates 3636570..3636827 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHJ24_RS17600 (OHJ24_17610) 3631292..3633487 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
OHJ24_RS17605 (OHJ24_17615) 3633675..3634241 - 567 WP_000651538.1 rhombosortase -
OHJ24_RS17610 (OHJ24_17620) 3634319..3635404 - 1086 WP_000049106.1 hypothetical protein -
OHJ24_RS17615 (OHJ24_17625) 3636174..3636563 - 390 WP_000607077.1 membrane protein Toxin
OHJ24_RS17620 (OHJ24_17630) 3636570..3636827 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
OHJ24_RS17625 (OHJ24_17635) 3637015..3638187 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
OHJ24_RS17630 (OHJ24_17640) 3638236..3639726 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
OHJ24_RS17635 (OHJ24_17645) 3639908..3640285 - 378 WP_001216380.1 50S ribosomal protein L17 -
OHJ24_RS17640 (OHJ24_17650) 3640304..3641311 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T262167 WP_000607077.1 NZ_CP109836:c3636563-3636174 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT262167 WP_001288210.1 NZ_CP109836:c3636827-3636570 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References