Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 278094..279049 Replicon chromosome
Accession NZ_CP109835
Organism Pseudomonas aeruginosa strain PALA26

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag PALA26_RS01285 Protein ID WP_170868735.1
Coordinates 278723..279049 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag PALA26_RS01280 Protein ID WP_023107584.1
Coordinates 278094..278651 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PALA26_RS01255 (PALA26_00248) 273151..273438 - 288 WP_003137130.1 hypothetical protein -
PALA26_RS01260 (PALA26_00249) 273530..274006 - 477 WP_003118626.1 MarR family transcriptional regulator -
PALA26_RS01265 (PALA26_00250) 274047..275537 - 1491 WP_003137133.1 UbiD family decarboxylase HudA -
PALA26_RS01270 (PALA26_00251) 275671..276357 - 687 WP_003106170.1 YoaK family protein -
PALA26_RS01275 (PALA26_00252) 276521..277453 - 933 WP_003084116.1 hypothetical protein -
PALA26_RS01280 (PALA26_00253) 278094..278651 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
PALA26_RS01285 (PALA26_00254) 278723..279049 + 327 WP_170868735.1 hypothetical protein Toxin
PALA26_RS01295 (PALA26_00257) 280491..281933 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12385.38 Da        Isoelectric Point: 9.1081

>T262160 WP_170868735.1 NZ_CP109835:278723-279049 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLRDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT262160 WP_023107584.1 NZ_CP109835:278094-278651 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References