Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 69639..70174 Replicon plasmid pSMBC31-93K
Accession NZ_CP109825
Organism Serratia marcescens strain SMBC31

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OHY99_RS25540 Protein ID WP_125460859.1
Coordinates 69887..70174 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8G2LES3
Locus tag OHY99_RS25535 Protein ID WP_038883487.1
Coordinates 69639..69890 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHY99_RS25515 (OHY99_25520) 65101..67179 + 2079 WP_264383982.1 ParB/RepB/Spo0J family partition protein -
OHY99_RS25520 (OHY99_25525) 67220..67660 + 441 WP_142076348.1 conjugation system SOS inhibitor PsiB -
OHY99_RS25525 (OHY99_25530) 67657..68382 + 726 WP_185742249.1 plasmid SOS inhibition protein A -
OHY99_RS25530 (OHY99_25535) 69097..69543 + 447 WP_264383983.1 dehydrogenase -
OHY99_RS25535 (OHY99_25540) 69639..69890 + 252 WP_038883487.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
OHY99_RS25540 (OHY99_25545) 69887..70174 + 288 WP_125460859.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OHY99_RS25545 (OHY99_25550) 70226..70504 + 279 WP_264383984.1 hypothetical protein -
OHY99_RS25550 (OHY99_25555) 70524..70997 + 474 WP_264383985.1 hypothetical protein -
OHY99_RS25555 (OHY99_25560) 71012..71365 + 354 WP_144302053.1 hypothetical protein -
OHY99_RS25560 (OHY99_25565) 72091..72468 + 378 WP_264383986.1 hypothetical protein -
OHY99_RS25565 (OHY99_25570) 72523..72942 + 420 WP_264383987.1 protein TraE -
OHY99_RS25570 (OHY99_25575) 72979..73326 + 348 WP_264383988.1 hypothetical protein -
OHY99_RS25575 (OHY99_25580) 73416..73679 + 264 WP_142076360.1 hypothetical protein -
OHY99_RS25580 (OHY99_25585) 74023..74532 + 510 WP_233074306.1 N-6 DNA methylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..93837 93837


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10891.93 Da        Isoelectric Point: 10.2278

>T262146 WP_125460859.1 NZ_CP109825:69887-70174 [Serratia marcescens]
MTYTVKFRESALKEWGKLDKSLQQQFAKKLKKCCENPHIPSAKLRGMPGCYKIKLRASGFRLVYEVIDDCLIIAVVAVGK
RERGDVYQLASERLK

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9182.46 Da        Isoelectric Point: 4.0338

>AT262146 WP_038883487.1 NZ_CP109825:69639-69890 [Serratia marcescens]
MPNIILSDTSASISELKKNPMETVGAGAGFPVAILNRNKPEFYCVPAALYEQMLDALDDQELVRLVNERRSEALVDIDLD
QFA

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References