Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 42037..42776 Replicon plasmid pSMBC31-93K
Accession NZ_CP109825
Organism Serratia marcescens strain SMBC31

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag OHY99_RS25375 Protein ID WP_264384012.1
Coordinates 42291..42776 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag OHY99_RS25370 Protein ID WP_264384011.1
Coordinates 42037..42303 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHY99_RS25355 (OHY99_25360) 37897..38967 - 1071 WP_264384008.1 hypothetical protein -
OHY99_RS25360 (OHY99_25365) 39298..40230 - 933 WP_264384009.1 S-4TM family putative pore-forming effector -
OHY99_RS25365 (OHY99_25370) 40234..41229 - 996 WP_264384010.1 nucleotidyltransferase -
OHY99_RS25370 (OHY99_25375) 42037..42303 + 267 WP_264384011.1 DUF1778 domain-containing protein Antitoxin
OHY99_RS25375 (OHY99_25380) 42291..42776 + 486 WP_264384012.1 GNAT family N-acetyltransferase Toxin
OHY99_RS25380 (OHY99_25385) 42958..43551 - 594 WP_264384013.1 hypothetical protein -
OHY99_RS25385 (OHY99_25390) 44255..44827 + 573 WP_264384014.1 fimbrial protein -
OHY99_RS25390 (OHY99_25395) 44888..45592 + 705 WP_264384015.1 fimbria/pilus periplasmic chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..93837 93837


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(75-151)

Antitoxin

Vibrio phage ICP1, Orf50

(2-87)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17642.53 Da        Isoelectric Point: 8.8745

>T262145 WP_264384012.1 NZ_CP109825:42291-42776 [Serratia marcescens]
VGCITAPVPLSSDHQLAEFVCGEVVLDDWLKQKGLKNQALGAARTFVVCKAETKRVLGFYSLATGSVNHVEATGNLRRNM
PDPIPVIILARLAVDISLRGRGLGADLLHDAVLRCYRVAENIGVRAIMVHALSDEAKAFYIHHGFKVSQTQERTLFLRVP
Q

Download         Length: 486 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10177.62 Da        Isoelectric Point: 4.4857

>AT262145 WP_264384011.1 NZ_CP109825:42037-42303 [Serratia marcescens]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACQAAENVILDRRVFNFNDEQYAEFIDMLDAPVTDEPVINKLL
TRKPQWDV

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References