Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4305468..4306137 Replicon chromosome
Accession NZ_CP109824
Organism Serratia marcescens strain SMBC31

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag OHY99_RS20875 Protein ID WP_025304123.1
Coordinates 4305468..4305890 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A8G2G4M4
Locus tag OHY99_RS20880 Protein ID WP_004931679.1
Coordinates 4305871..4306137 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHY99_RS20855 (OHY99_20860) 4301357..4301875 + 519 WP_025304119.1 flavodoxin FldB -
OHY99_RS20860 (OHY99_20865) 4301913..4303277 - 1365 WP_197837477.1 cell envelope integrity protein CreD -
OHY99_RS20865 (OHY99_20870) 4303358..4304776 - 1419 WP_169540605.1 two-component system sensor histidine kinase CreC -
OHY99_RS20870 (OHY99_20875) 4304773..4305468 - 696 WP_025304122.1 two-component system response regulator CreB -
OHY99_RS20875 (OHY99_20880) 4305468..4305890 - 423 WP_025304123.1 protein YgfX Toxin
OHY99_RS20880 (OHY99_20885) 4305871..4306137 - 267 WP_004931679.1 FAD assembly factor SdhE Antitoxin
OHY99_RS20885 (OHY99_20890) 4306458..4307450 + 993 WP_025304124.1 tRNA-modifying protein YgfZ -
OHY99_RS20890 (OHY99_20895) 4307489..4307986 - 498 WP_025304125.1 DUF2165 domain-containing protein -
OHY99_RS20895 (OHY99_20900) 4308137..4308811 - 675 WP_033639467.1 hemolysin III family protein -
OHY99_RS20900 (OHY99_20905) 4308995..4309603 + 609 WP_025304127.1 HD domain-containing protein -
OHY99_RS20905 (OHY99_20910) 4309643..4310569 - 927 WP_025304128.1 ribokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 16525.62 Da        Isoelectric Point: 10.8432

>T262142 WP_025304123.1 NZ_CP109824:c4305890-4305468 [Serratia marcescens]
VAQWRCDIRISWRTQLFSLLTHGVLILLILISPWPEGYGPLWLVLLTLVVFQCIRSQKRIAAVQGELRLLADRRFSWHGR
EWRLAKKPWMPGYGLLLTLQPMEGKKRRRLWLASDCMSKEEWRHLRQLLLYPPAGNGEEP

Download         Length: 423 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10387.89 Da        Isoelectric Point: 4.7921

>AT262142 WP_004931679.1 NZ_CP109824:c4306137-4305871 [Serratia marcescens]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLNDADKALFIRLLECDDPDLFNWLMNHGAPQDGELQRMVTLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References