Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2006773..2006913 Replicon chromosome
Accession NZ_CP109824
Organism Serratia marcescens strain SMBC31

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2006817..2006913 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2006773..2006913 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OHY99_RS09790 (OHY99_09790) 2002043..2002438 + 396 WP_049203470.1 RidA family protein -
OHY99_RS09795 (OHY99_09795) 2002595..2003548 + 954 WP_141997776.1 prolyl aminopeptidase -
OHY99_RS09800 (OHY99_09800) 2003579..2003809 - 231 WP_043141621.1 DNA polymerase III subunit theta -
OHY99_RS09805 (OHY99_09805) 2004154..2004672 + 519 WP_025302449.1 non-heme ferritin -
OHY99_RS09810 (OHY99_09810) 2004997..2005380 + 384 WP_043141618.1 CopC domain-containing protein YobA -
OHY99_RS09815 (OHY99_09815) 2005383..2006264 + 882 WP_049209425.1 copper homeostasis membrane protein CopD -
OHY99_RS09820 (OHY99_09820) 2006334..2006675 + 342 WP_025302452.1 YebY family protein -
- 2006773..2006913 - 141 - - Antitoxin
- 2006817..2006913 + 97 - - Toxin
OHY99_RS09825 (OHY99_09825) 2007027..2007185 - 159 WP_238476101.1 hypothetical protein -
OHY99_RS09830 (OHY99_09830) 2007296..2008354 + 1059 WP_197835490.1 acyltransferase -
OHY99_RS09835 (OHY99_09835) 2009031..2010128 + 1098 WP_264383917.1 hypothetical protein -
OHY99_RS09840 (OHY99_09840) 2010135..2011172 - 1038 WP_264383603.1 IS630 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2010135..2011172 1037


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T262134 NZ_CP109824:2006817-2006913 [Serratia marcescens]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT262134 NZ_CP109824:c2006913-2006773 [Serratia marcescens]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References