Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 281950..282572 Replicon chromosome
Accession NZ_CP109812
Organism Stenotrophomonas sp. SBJS02

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag FQS62_RS01265 Protein ID WP_049431373.1
Coordinates 282282..282572 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag FQS62_RS01260 Protein ID WP_226053677.1
Coordinates 281950..282243 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FQS62_RS01235 (FQS62_001235) 277063..277860 + 798 WP_049448190.1 enoyl-CoA hydratase -
FQS62_RS01240 (FQS62_001240) 277857..279032 + 1176 WP_208043726.1 enoyl-CoA hydratase/isomerase family protein -
FQS62_RS01245 (FQS62_001245) 279029..279919 + 891 WP_208043727.1 3-hydroxyisobutyrate dehydrogenase -
FQS62_RS01250 (FQS62_001250) 280147..280572 - 426 WP_004153735.1 organic hydroperoxide resistance protein -
FQS62_RS01255 (FQS62_001255) 280684..281664 - 981 WP_208043547.1 cation transporter -
FQS62_RS01260 (FQS62_001260) 281950..282243 - 294 WP_226053677.1 putative addiction module antidote protein Antitoxin
FQS62_RS01265 (FQS62_001265) 282282..282572 - 291 WP_049431373.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
FQS62_RS01270 (FQS62_001270) 282718..284499 - 1782 WP_208043546.1 peptidoglycan-binding protein -
FQS62_RS01275 (FQS62_001275) 284542..284946 - 405 WP_226053678.1 lysozyme inhibitor LprI family protein -
FQS62_RS01280 (FQS62_001280) 285212..286075 + 864 WP_157804554.1 lysozyme inhibitor LprI family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10850.47 Da        Isoelectric Point: 11.8946

>T262128 WP_049431373.1 NZ_CP109812:c282572-282282 [Stenotrophomonas sp. SBJS02]
MAILQATETFTRWLRGLNDSRARGVIVERLQRVARGLEGDVRSVGHGVSELRINHGPGYRVYFTRRGRSIVVLLHGGDKS
SQRRDIEKAVRLAELL

Download         Length: 291 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10107.50 Da        Isoelectric Point: 6.7225

>AT262128 WP_226053677.1 NZ_CP109812:c282243-281950 [Stenotrophomonas sp. SBJS02]
MSKLKTIPFDPADYLDDDVAIAAYLSEALAAGDAGHFQEALGTVARARGMGGVAEVSGLGRESLYKALRPGAHPRFDTVQ
RVLSALGVHLTVQAGKA

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References